Literature DB >> 891875

Candletoxins A and B, 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, from the irritant latex of Euphoria poisonii Pax.

R J Schmidt, F J Evans.   

Abstract

2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, known as candletoxins A and B, were isolated from the irritant latex of Euphorbia poisonii Pax. Compound A was identified as 12-deoxy-phorbol-13-O-phenylacetate-16-O-alpha-methyl-butyrate-20-acetate, and compound B was the C-20 desacetyl analogue.

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Year:  1977        PMID： 891875     DOI： 10.1007/bf01922325

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  2 in total

1.  The succulent euphorbias of Nigeria. Part I.

Authors:  F J Evans; A D Kinghorn
Journal:  Lloydia       Date:  1975 Jul-Aug

2.  [On the biologically active compounds of euphorbiaceae. I. Skinirritant and cocarcinogenic factors from Euphorbia cooperi N.E.Br (author's transl)].

Authors:  M Gschwendt; E Hecker
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1973-12-28
  2 in total
  3 in total

1.  On the active principles of the spurge family (Euphorbiaceae). V. Extremely skin-irritant and moderately tumor-promoting diterpene esters from Euphorbia resinifera Berg.

Authors:  M Hergenhahn; S Kusumoto; E Hecker
Journal:  J Cancer Res Clin Oncol       Date:  1984       Impact factor: 4.553

2.  An assay procedure for the comparative irritancy testing of esters in the tigliane and daphnane series.

Authors:  F J Evans; R J Schmidt
Journal:  Inflammation       Date:  1979-07       Impact factor: 4.092

3.  Skin irritant effects of esters of phorbol and related polyols.

Authors:  R J Schmidt; F J Evans
Journal:  Arch Toxicol       Date:  1980-04       Impact factor: 5.153
  3 in total

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