Literature DB >> 891780

The metabolism of the male antifertility agent 1-amino-3-chloropropan-2-ol in the rat.

A R Jones, C Murcott, D H Milton, J Flynn.   

Abstract

Entities:  

Keywords:  Alcohols; Alpha-chlorohydrin--analysis; Animals, Laboratory; Biology; Clinical Research; Contraception; Contraceptive Agents; Contraceptive Agents, Male; Family Planning; Ingredients And Chemicals; Metabolic Effects; Organic Chemicals; Physiology; Research Methodology; Sperm Maturation Blocking Agents; Steroid Metabolic Effects

Mesh：

Substances：

Year:  1977        PMID： 891780     DOI： 10.1007/bf01951290

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


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  14 in total

1.  Identification of the biochemical lesion produced by alpha-chlorohydrin in spermatozoa.

Authors:  H Mohri; D A Suter; P D Brown-Woodman; I G White; D D Ridley
Journal:  Nature       Date:  1975-05-01       Impact factor: 49.962

2.  The metabolism of 3-chloro,- 3-bromo- and 3-iodoprpan-1,2-diol in rats and mice.

Authors:  A R Jones
Journal:  Xenobiotica       Date:  1975-03       Impact factor: 1.908

3.  The antifertility effects of alpha-chlorohydrins and their stereo-isomers in male rats.

Authors:  H Jackson; B Robinson
Journal:  Chem Biol Interact       Date:  1976-05       Impact factor: 5.192

4.  Structure-activity studies with chlorohydrins as orally active male antifertility agents.

Authors:  R Paul; R P Williams; E Cohen
Journal:  Contraception       Date:  1974-05       Impact factor: 3.375

5.  A new orally active male antifertility agent.

Authors:  J A Coppola; R J Saldarini
Journal:  Contraception       Date:  1974-05       Impact factor: 3.375

6.  Male antifertility compounds: structure and activity relationships of U-5897, U-l5,646 and related substances.

Authors:  R J Ericsson; G A Youngdale
Journal:  J Reprod Fertil       Date:  1970-03

7.  Is glycidol an active intermediate in the antifertility action of alpha-chlorhydrin in male rats?

Authors:  H Jackson; I S Campbell; A R Jones
Journal:  Nature       Date:  1970-04-04       Impact factor: 49.962

8.  Post-testicular antifertility effects of epichlorohydrin and 2,3-xpoxypropanol.

Authors:  J D Hahn
Journal:  Nature       Date:  1970-04-04       Impact factor: 49.962

9.  The oxidative metabolism of alpha-chlorohydrin and the chemical induction of spermatocoeles.

Authors:  A R Jones; C Murcott
Journal:  Experientia       Date:  1976-09-15

10.  The rate of acetaldehyde metabolism in rabbits treated with antabuse (tetraethylthiuramdisulphide).

Authors:  J HALD; V LARSEN
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1949-10
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