Literature DB >> 891719

Kinetic behaviour of microsomal styrene monooxygenase and styrene epoxide hydratase in different animal species.

G Belvedere, L Cantoni, T Facchinetti, M Salmona.   

Abstract

The apparent Km and Vmax values of styrene epoxide forming monooxygenase and styrene epoxide hydratase have been evaluated in the liver microsomes of male rats, mice, guinea-pigs and rabbits. Epoxide hydratase gave much higher and more uniform Km values than the monooxygenase in the species considered.

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Year:  1977        PMID： 891719     DOI： 10.1007/bf01944141

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

1.  A specific gas chromatographic method for the determination of microsomal styrene monooxygenase and styrene epoxide hydratase activities.

Authors:  G Belvedere; J Pachecka; L Cantoni; E Mussini; M Salmona
Journal:  J Chromatogr       Date:  1976-04-07

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Separation, purification, and properties of multiple forms of cytochrome P-450 from the liver microsomes of phenobarbital-treated mice.

Authors:  M T Huang; S B West; A Y Lu
Journal:  J Biol Chem       Date:  1976-08-10       Impact factor: 5.157

Review 4.  Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.

Authors:  F Oesch
Journal:  Xenobiotica       Date:  1973-05       Impact factor: 1.908

5.  Arene oxides: a new aspect of drug metabolism.

Authors:  D M Jerina; J W Daly
Journal:  Science       Date:  1974-08-16       Impact factor: 47.728

6.  Differences among the action of phenobarbital, methylcholanthrene and male sex hormone on microsomal drug-metabolizing enzyme systems of rat liver.

Authors:  R Kato; M Takayanaghi
Journal:  Jpn J Pharmacol       Date:  1966-12

7.  Induction of multiple forms of mouse liver cytochrome P-450. Evidence for genetically controlled de novo protein synthesis in response to treatment with beta-naphthoflavone or phenobarbital.

Authors:  D A Haugen; M J Coon
Journal:  J Biol Chem       Date:  1976-03-25       Impact factor: 5.157
  7 in total
  3 in total

1.  Human exposure to styrene. III. Elimination kinetics of urinary mandelic and phenylglyoxylic acids after single experimental exposure.

Authors:  M P Guillemin; D Bauer
Journal:  Int Arch Occup Environ Health       Date:  1979-11       Impact factor: 3.015

2.  Non-linear kinetics of microsomal styrene monooxygenase after phenobarbital pre-treatment.

Authors:  R Cantoni; E Vignazia; G Belvedere; L Cantoni; M Salmona
Journal:  Experientia       Date:  1980-06-15

3.  In vitro kinetics of styrene and styrene oxide metabolism in rat, mouse, and human.

Authors:  A L Mendrala; P W Langvardt; K D Nitschke; J F Quast; R J Nolan
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153
  3 in total

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