Literature DB >> 8914775

A new procedure for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes supernatant.

E M Mascini1, M A Hazenberg, L A Verhage, S E Holm, J Verhoef, H van Dijk.   

Abstract

An important role in the pathogenesis of invasive group A streptococcal disease has been ascribed to the production of streptococcal pyrogenic exotoxin A. We present a new technique for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes NY-5 supernate, which is highly efficient with respect to yield (35%), purity (> or = 99%), and time.

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Year:  1996        PMID： 8914775      PMCID： PMC170447          DOI： 10.1128/cdli.3.6.779-781.1996

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  19 in total

1.  Molecular epidemiologic analysis of the type A streptococcal exotoxin (erythrogenic toxin) gene (speA) in clinical Streptococcus pyogenes strains.

Authors:  C E Yu; J J Ferretti
Journal:  Infect Immun       Date:  1989-12       Impact factor: 3.441

2.  Nucleotide sequence of the type A streptococcal exotoxin (erythrogenic toxin) gene from Streptococcus pyogenes bacteriophage T12.

Authors:  C R Weeks; J J Ferretti
Journal:  Infect Immun       Date:  1986-04       Impact factor: 3.441

Review 3.  The staphylococcal enterotoxins and their relatives.

Authors:  P Marrack; J Kappler
Journal:  Science       Date:  1990-05-11       Impact factor: 47.728

4.  Further purification of group A streptococcal pyrogenic exotoxin and characterization of the purified toxin.

Authors:  C M Cunningham; E L Barsumian; D W Watson
Journal:  Infect Immun       Date:  1976-09       Impact factor: 3.441

5.  Association of phenotypic and genotypic characteristics of invasive Streptococcus pyogenes isolates with clinical components of streptococcal toxic shock syndrome.

Authors:  D F Talkington; B Schwartz; C M Black; J K Todd; J Elliott; R F Breiman; R R Facklam
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

6.  Purification and characterization of streptococcal erythrogenic toxin type A produced by Streptococcus pyogenes strain NY-5 cultured in the synthetic medium NCTC-135. Comparison with the dialyzed medium (TP medium)-derived toxin.

Authors:  Y Kamezawa; T Nakahara
Journal:  Microbiol Immunol       Date:  1989       Impact factor: 1.955

7.  Purification and characterization of erythrogenic toxins. IV. Communication: mitogenic activity of erythrogenic toxin produced by Streptococcus pyogenes strain NY-5.

Authors:  H Knöll; V Hríbalová; D Gerlach; W Köhler
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1981-12

8.  Streptococcal outbreaks and erythrogenic toxin type A.

Authors:  W Köhler; D Gerlach; H Knöll
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1987-08

9.  Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A.

Authors:  D L Stevens; M H Tanner; J Winship; R Swarts; K M Ries; P M Schlievert; E Kaplan
Journal:  N Engl J Med       Date:  1989-07-06       Impact factor: 91.245

10.  A purified group A streptococcal pyrogenic exotoxin. Physiochemical and biological properties including the enhancement of susceptibility to endotoxin lethal shock.

Authors:  Y B Kim; D W Watson
Journal:  J Exp Med       Date:  1970-03-01       Impact factor: 14.307
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  2 in total

1.  Relative avidities of human immunoglobulin G antibodies for streptococcal pyrogenic exotoxins A and B.

Authors:  E M Mascini; M Jansze; J Verhoef; H van Dijk
Journal:  Clin Diagn Lab Immunol       Date:  1999-11

2.  Invasive and noninvasive group A streptococcal isolates with different speA alleles in The Netherlands: genetic relatedness and production of pyrogenic exotoxins A and B.

Authors:  E M Mascini; M Jansze; L M Schouls; A C Fluit; J Verhoef; H van Dijk
Journal:  J Clin Microbiol       Date:  1999-11       Impact factor: 5.948
  2 in total

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