BACKGROUND: Accurate knowledge of polyp size is important in assessing cancer risk in both clinical studies and individual patients. We sought to determine if a difference exists between the endoscopic estimation of colon polyp size and the actual measurement after removal. METHODS: We measured polyps in a systematic fashion. Using open biopsy forceps as a guide, the largest diameter of 31 pedunculated polyps was estimated endoscopically. The polyp was then removed by snare polypectomy and directly measured by a technician who was blinded to the endoscopic estimate. Each polyp was also measured after formalin fixation by a pathologist who was blinded to previous measurements. RESULTS: There was a significant difference between the endoscopic estimates and the postpolypectomy measurements. Endoscopic estimates on average were 1.6 mm greater than the postpolypectomy measurements (p< 0.05), representing an 18% difference. Twenty-three of the 31 (74%) endoscopic estimates were larger than the postpolypectomy measurements. There was not a significant difference between the postpolypectomy and postfixation measurements. CONCLUSIONS: The size of polyps measured endoscopically is significantly larger on average than postpolypectomy measurements. This is most likely due to factors involved in the removal of the in vivo polyp.
BACKGROUND: Accurate knowledge of polyp size is important in assessing cancer risk in both clinical studies and individual patients. We sought to determine if a difference exists between the endoscopic estimation of colon polyp size and the actual measurement after removal. METHODS: We measured polyps in a systematic fashion. Using open biopsy forceps as a guide, the largest diameter of 31 pedunculated polyps was estimated endoscopically. The polyp was then removed by snare polypectomy and directly measured by a technician who was blinded to the endoscopic estimate. Each polyp was also measured after formalin fixation by a pathologist who was blinded to previous measurements. RESULTS: There was a significant difference between the endoscopic estimates and the postpolypectomy measurements. Endoscopic estimates on average were 1.6 mm greater than the postpolypectomy measurements (p< 0.05), representing an 18% difference. Twenty-three of the 31 (74%) endoscopic estimates were larger than the postpolypectomy measurements. There was not a significant difference between the postpolypectomy and postfixation measurements. CONCLUSIONS: The size of polyps measured endoscopically is significantly larger on average than postpolypectomy measurements. This is most likely due to factors involved in the removal of the in vivo polyp.
Authors: David Burling; Steve Halligan; Douglas G Altman; Wendy Atkin; Clive Bartram; Helen Fenlon; Andrea Laghi; Jaap Stoker; Stuart Taylor; Roger Frost; Guido Dessey; Melinda De Villiers; Jasper Florie; Shane Foley; Lesley Honeyfield; Riccardo Iannaccone; Teresa Gallo; Clive Kay; Philippe Lefere; Andrew Lowe; Filipo Mangiapane; Jesse Marrannes; Emmanuele Neri; Giulia Nieddu; David Nicholson; Alan O'Hare; Sante Ori; Benedetta Politi; Martin Poulus; Daniele Regge; Lisa Renaut; Velauthan Rudralingham; Saverio Signoretta; Paola Vagli; Victor Van der Hulst; Jane Williams-Butt Journal: Eur Radiol Date: 2006-04-25 Impact factor: 5.315
Authors: S Punwani; S Halligan; P Irving; S Bloom; A Bungay; R Greenhalgh; J Godbold; S A Taylor; D G Altman Journal: Eur Radiol Date: 2008-01-04 Impact factor: 5.315
Authors: Jae Hyun Kim; Seun Ja Park; Jong Hoon Lee; Tae Oh Kim; Hyun Jin Kim; Hyung Wook Kim; Sang Heon Lee; Dong Hoon Baek; Busan Ulsan Gyeongnam Intestinal Study Group Society Bigs Journal: World J Gastroenterol Date: 2016-03-21 Impact factor: 5.742
Authors: Ayso H de Vries; Shandra Bipat; Evelien Dekker; Marjolein H Liedenbaum; Jasper Florie; Paul Fockens; Roel van der Kraan; Elizabeth M Mathus-Vliegen; Johannes B Reitsma; Roel Truyen; Frans M Vos; Aeilko H Zwinderman; Jaap Stoker Journal: Eur Radiol Date: 2009-12-22 Impact factor: 5.315