Literature DB >> 8900063

Cloning and nucleotide sequence of the mphB gene for macrolide 2'-phosphotransferase II in Escherichia coli.

N Noguchi1, J Katayama, K O'Hara.   

Abstract

Macrolide 2'-phosphotransferase II [MPH(2')II] inactivates macrolide antibiotics. The mphB gene for MPH(2')II was cloned from Escherichia coli and sequenced. Analysis of the nucleotide sequence indicated that mphB encoded a protein of 302 amino acids with a molecular mass of 34483 Da. The carboxy terminal region of the deduced protein contained a sequence that resembled a conserved functional domain in aminoglycoside phosphotransferases.

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Year:  1996        PMID： 8900063     DOI： 10.1111/j.1574-6968.1996.tb08530.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  14 in total

Review 1.  Nomenclature for macrolide and macrolide-lincosamide-streptogramin B resistance determinants.

Authors:  M C Roberts; J Sutcliffe; P Courvalin; L B Jensen; J Rood; H Seppala
Journal:  Antimicrob Agents Chemother       Date:  1999-12       Impact factor: 5.191

2.  Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance.

Authors:  A Alonso; P Sanchez; J L Martínez
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

3.  Identification of functional amino acids in the macrolide 2'-phosphotransferase II.

Authors:  K Taniguchi; A Nakamura; K Tsurubuchi; A Ishii; K O'Hara; T Sawai
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

4.  Streptothricin biosynthesis is catalyzed by enzymes related to nonribosomal peptide bond formation.

Authors:  M A Fernández-Moreno; C Vallín; F Malpartida
Journal:  J Bacteriol       Date:  1997-11       Impact factor: 3.490

5.  Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage.

Authors:  A Tait-Kamradt; T Davies; M Cronan; M R Jacobs; P C Appelbaum; J Sutcliffe
Journal:  Antimicrob Agents Chemother       Date:  2000-08       Impact factor: 5.191

6.  Regulation of transcription of the mph(A) gene for macrolide 2'-phosphotransferase I in Escherichia coli: characterization of the regulatory gene mphR(A).

Authors:  N Noguchi; K Takada; J Katayama; A Emura; M Sasatsu
Journal:  J Bacteriol       Date:  2000-09       Impact factor: 3.490

7.  Antimicrobial Susceptibility Testing and Tentative Epidemiological Cutoff Values for Five Bacillus Species Relevant for Use as Animal Feed Additives or for Plant Protection.

Authors:  Yvonne Agersø; Birgitte Stuer-Lauridsen; Karin Bjerre; Michelle Geervliet Jensen; Eric Johansen; Mads Bennedsen; Elke Brockmann; Bea Nielsen
Journal:  Appl Environ Microbiol       Date:  2018-09-17       Impact factor: 4.792

Review 8.  Resistance to Macrolide Antibiotics in Public Health Pathogens.

Authors:  Corey Fyfe; Trudy H Grossman; Kathy Kerstein; Joyce Sutcliffe
Journal:  Cold Spring Harb Perspect Med       Date:  2016-10-03       Impact factor: 6.915

9.  The mef(A) gene predominates among seven macrolide resistance genes identified in gram-negative strains representing 13 genera, isolated from healthy Portuguese children.

Authors:  K K Ojo; C Ulep; N Van Kirk; H Luis; M Bernardo; J Leitao; M C Roberts
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

Review 10.  Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics.

Authors:  Marilyn C Roberts
Journal:  Mol Biotechnol       Date:  2004-09       Impact factor: 2.695
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