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Literature DB >> 88955

Acycloguanosine: antiviral activity in the rabbit cornea.

Abstract

We describe experiments, using the multiple microinoculation technique, to produce superficial herpes simplex keratitis in the rabbit cornea, which showed a potent antiviral effect of acycloguanosine.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1979 PMID： 88955 PMCID： PMC1043502 DOI： 10.1136/bjo.63.6.422

Source DB: PubMed Journal: Br J Ophthalmol ISSN： 0007-1161 Impact factor: 4.638

7 in total

1. THERAPEUTIC CONSIDERATIONS IN OCULAR VACCINIA.

Authors: B R JONES; M K AL-HUSSAINI
Journal: Trans Ophthalmol Soc U K Date: 1963

2. Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.

Authors: G B Elion; P A Furman; J A Fyfe; P de Miranda; L Beauchamp; H J Schaeffer
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

3. 9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.

Authors: H J Schaeffer; L Beauchamp; P de Miranda; G B Elion; D J Bauer; P Collins
Journal: Nature Date: 1978-04-13 Impact factor: 49.962

4. Herpes simplex keratitis: animal models to guide the selection and optimal delivery of antiviral chemotherapy.

Authors: M G Falcon; B R Jones
Journal: J Antimicrob Chemother Date: 1977-03 Impact factor: 5.790

5. Antivirals for the therapy of herpetic eye disease.

Authors: M G Falcon; B R Jones
Journal: Trans Ophthalmol Soc U K Date: 1977-07

6. Treatment of experimental herpes simplex keratitis with acycloguanosine.

Authors: D J Bauer; P Collins; W E Tucker; A W Macklin
Journal: Br J Ophthalmol Date: 1979-06 Impact factor: 4.638

7. Efficacy of acycloguanosine (Wellcome 248U) against herpes-simplex corneal ulcers.

Authors: B R Jones; D J Coster; P N Fison; G M Thompson; L M Cobo; M G Falcon
Journal: Lancet Date: 1979-02-03 Impact factor: 79.321

7 in total

1. Comparative in vitro imunotoxicology of acyclovir and other antiviral agents.

Authors: R W Steele; D J Marmer; R E Keeney
Journal: Infect Immun Date: 1980-06 Impact factor: 3.441

2. A comparison of acyclovir and idoxuridine as treatment for ulcerative herpetic keratitis.

Authors: D J Coster; K R Wilhelmus; R Michaud; B R Jones
Journal: Br J Ophthalmol Date: 1980-10 Impact factor: 4.638

3. Comparative trial of acyclovir and adenine arabinoside in the treatment of herpes simplex corneal ulcers.

Authors: J McGill; P Tormey; C B Walker
Journal: Br J Ophthalmol Date: 1981-09 Impact factor: 4.638

4. Uptake, distribution, and anabolism of acyclovir in herpes simplex virus-infected mice.

Authors: K K Biron; J E Noblin; P de Miranda; G B Elion
Journal: Antimicrob Agents Chemother Date: 1982-01 Impact factor: 5.191

5. Acyclovir treatment in stromal herpetic keratitis.

Authors: J A Oosterhuis; R van Ganswijk; J Versteeg
Journal: Doc Ophthalmol Date: 1983-12-15 Impact factor: 2.379

6. Acyclovir therapy of neonatal herpes simplex virus type 2 infections in rabbits.

Authors: S E Sicher; J O Oh
Journal: Antimicrob Agents Chemother Date: 1981-10 Impact factor: 5.191

Review 7. Acyclovir. A review of its pharmacodynamic properties and therapeutic efficacy.

Authors: D M Richards; A A Carmine; R N Brogden; R C Heel; T M Speight; G S Avery
Journal: Drugs Date: 1983-11 Impact factor: 9.546

7 in total