Literature DB >> 8894589

Effects of ginsenosides on impaired performance caused by scopolamine in rats.

Y Yamaguchi1, M Higashi, H Kobayashi.   

Abstract

The effects of five structurally different ginsenosides on the performance impaired by scopolamine in rats were studied in a radial-arm maze. Ginsenoside Re had an ameliorating effect, but the ginsenosides, 20-O-glucosyl-protopanaxadiol, F2, Rf, and Rh1, did not. We reported previously that ginsenoside Rg1 had an ameliorating effect but that ginsenosides Rb1 and Rd did not (Yamaguchi et al., 1995, Psychoneuroendocrinology 20, 645). The sugar moieties at C(6) and C(20), which are possessed by Re and Rg1, seem to be indispensable for an ameliorating effect on the performance impaired by scopolamine.

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Year:  1996        PMID: 8894589     DOI: 10.1016/0014-2999(96)00597-3

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  5 in total

1.  Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds.

Authors:  Lars P Christensen; Martin Jensen
Journal:  J Nat Med       Date:  2008-12-16       Impact factor: 2.343

2.  Ginseng derivative ocotillol enhances neuronal activity through increased glutamate release: a possible mechanism underlying increased spontaneous locomotor activity of mice.

Authors:  Z-J Wang; L Sun; W Peng; S Ma; C Zhu; F Fu; T Heinbockel
Journal:  Neuroscience       Date:  2011-08-12       Impact factor: 3.590

Review 3.  Current evaluation of the millennium phytomedicine- ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine.

Authors:  Lee Jia; Yuqing Zhao; Xing-Jie Liang
Journal:  Curr Med Chem       Date:  2009       Impact factor: 4.530

Review 4.  Preventing Dementia Using Saffron, The Kampo Medicine, Kamiuntanto, and Their Combination, Kamiuntantokabankoka.

Authors:  Kenny Kuchta; Kosuke Aritake; Yoshihiro Urade; Nguyen Huu Tung; Chun-Su Yuan; Yui Sasaki; Koichi Shimizu; Yukihiro Shoyama
Journal:  Front Pharmacol       Date:  2022-03-04       Impact factor: 5.810

5.  Effects of processing method on the pharmacokinetics and tissue distribution of orally administered ginseng.

Authors:  Jianbo Chen; Meijia Li; Lixue Chen; Yufang Wang; Shanshan Li; Yuwei Zhang; Lei Zhang; Mingjie Song; Chang Liu; Mei Hua; Yinshi Sun
Journal:  J Ginseng Res       Date:  2017-01-11       Impact factor: 6.060

  5 in total

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