Literature DB >> 8893827

Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors.

S Thaisrivongs1, H I Skulnick, S R Turner, J W Strohbach, R A Tommasi, P D Johnson, P A Aristoff, T M Judge, R B Gammill, J K Morris, K R Romines, R A Chrusciel, R R Hinshaw, K T Chong, W G Tarpley, S M Poppe, D E Slade, J C Lynn, M M Horng, P K Tomich, E P Seest, L A Dolak, W J Howe, G M Howard, K D Watenpaugh.   

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Year:  1996        PMID： 8893827     DOI： 10.1021/jm960541s

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  14 in total

1.  The maximal affinity of ligands.

Authors:  I D Kuntz; K Chen; K A Sharp; P A Kollman
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

2.  Inhibition and substrate recognition--a computational approach applied to HIV protease.

Authors:  H M Vinkers; M R de Jonge; E D Daeyaert; J Heeres; L M H Koymans; J H van Lenthe; P J Lewi; H Timmerman; P A J Janssen
Journal:  J Comput Aided Mol Des       Date:  2003-09       Impact factor: 3.686

3.  Classification of HIV protease inhibitors on the basis of their antiviral potency using radial basis function neural networks.

Authors:  S J Patankar; P C Jurs
Journal:  J Comput Aided Mol Des       Date:  2003 Feb-Apr       Impact factor: 3.686

4.  Rationale for more diverse inhibitors in competition with substrates in HIV-1 protease.

Authors:  Nevra Ozer; Celia A Schiffer; Turkan Haliloglu
Journal:  Biophys J       Date:  2010-09-08       Impact factor: 4.033

5.  Novel method for probing the specificity binding profile of ligands: applications to HIV protease.

Authors:  Woody Sherman; Bruce Tidor
Journal:  Chem Biol Drug Des       Date:  2008-03-31       Impact factor: 2.817

6.  In vitro combination of PNU-140690, a human immunodeficiency virus type 1 protease inhibitor, with ritonavir against ritonavir-sensitive and -resistant clinical isolates.

Authors:  K T Chong; P J Pagano
Journal:  Antimicrob Agents Chemother       Date:  1997-11       Impact factor: 5.191

7.  Oxidative degradation of a sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrone in aqueous/organic cosolvent mixtures.

Authors:  Susan W Hovorka; Michael J Hageman; Christian Schöneich
Journal:  Pharm Res       Date:  2002-04       Impact factor: 4.200

8.  Prediction of potency of protease inhibitors using free energy simulations with polarizable quantum mechanics-based ligand charges and a hybrid water model.

Authors:  Debananda Das; Yasuhiro Koh; Yasushi Tojo; Arun K Ghosh; Hiroaki Mitsuya
Journal:  J Chem Inf Model       Date:  2009-12       Impact factor: 4.956

9.  Predicting drug resistance of the HIV-1 protease using molecular interaction energy components.

Authors:  Tingjun Hou; Wei Zhang; Jian Wang; Wei Wang
Journal:  Proteins       Date:  2009-03

10.  Evaluating the potency of HIV-1 protease drugs to combat resistance.

Authors:  Tingjun Hou; William A McLaughlin; Wei Wang
Journal:  Proteins       Date:  2008-05-15
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