Literature DB >> 8892939

Possible involvement of double-stranded RNA-activated protein kinase in cell death by influenza virus infection.

T Takizawa1, K Ohashi, Y Nakanishi.   

Abstract

We reported previously that influenza virus infection induces the apoptotic death of HeLa cells associated with activation of the Fas gene. In this report, we show that transfection with a PKR having a point mutation in the catalytic domain of K at 296 to R suppressed both the augmented expression of Fas and cell death by influenza virus infection. These results suggested the involvement of PKR in influenza virus-induced cell death.

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Year:  1996        PMID： 8892939      PMCID： PMC190888     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  33 in total

1.  The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins.

Authors:  T G Lee; N Tang; S Thompson; J Miller; M G Katze
Journal:  Mol Cell Biol       Date:  1994-04       Impact factor: 4.272

2.  In vivo induction of apoptosis by influenza virus.

Authors:  I Mori; T Komatsu; K Takeuchi; K Nakakuki; M Sudo; Y Kimura
Journal:  J Gen Virol       Date:  1995-11       Impact factor: 3.891

3.  Programmed cell death (apoptosis) in human monocytes infected by influenza A virus.

Authors:  H Fesq; M Bacher; M Nain; D Gemsa
Journal:  Immunobiology       Date:  1994-02       Impact factor: 3.144

4.  Apoptosis: a mechanism of cell killing by influenza A and B viruses.

Authors:  V S Hinshaw; C W Olsen; N Dybdahl-Sissoko; D Evans
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

5.  Transcription stimulation of the Fas-encoding gene by nuclear factor for interleukin-6 expression upon influenza virus infection.

Authors:  N Wada; M Matsumura; Y Ohba; N Kobayashi; T Takizawa; Y Nakanishi
Journal:  J Biol Chem       Date:  1995-07-28       Impact factor: 5.157

6.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

7.  Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Authors:  A Kumar; J Haque; J Lacoste; J Hiscott; B R Williams
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

8.  Activation of the apoptotic Fas antigen-encoding gene upon influenza virus infection involving spontaneously produced beta-interferon.

Authors:  T Takizawa; R Fukuda; T Miyawaki; K Ohashi; Y Nakanishi
Journal:  Virology       Date:  1995-06-01       Impact factor: 3.616

9.  Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation.

Authors:  G N Barber; M Wambach; S Thompson; R Jagus; M G Katze
Journal:  Mol Cell Biol       Date:  1995-06       Impact factor: 4.272

10.  Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.

Authors:  Y L Yang; L F Reis; J Pavlovic; A Aguzzi; R Schäfer; A Kumar; B R Williams; M Aguet; C Weissmann
Journal:  EMBO J       Date:  1995-12-15       Impact factor: 11.598
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  34 in total

1.  Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.

Authors:  J Gil; J Alcamí; M Esteban
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

Review 2.  Molecular pathways in virus-induced cytokine production.

Authors:  T H Mogensen; S R Paludan
Journal:  Microbiol Mol Biol Rev       Date:  2001-03       Impact factor: 11.056

3.  Molecular mechanism by which palmitate inhibits PKR autophosphorylation.

Authors:  Hyunju Cho; Shayantani Mukherjee; Pratheeba Palasuberniam; Lisa Pillow; Betul Bilgin; Catherine Nezich; S Patrick Walton; Michael Feig; Christina Chan
Journal:  Biochemistry       Date:  2011-01-24       Impact factor: 3.162

4.  Rabies virus infects mouse and human lymphocytes and induces apoptosis.

Authors:  M I Thoulouze; M Lafage; J A Montano-Hirose; M Lafon
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

5.  Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18.

Authors:  K U Kumar; S P Srivastava; R J Kaufman
Journal:  Mol Cell Biol       Date:  1999-02       Impact factor: 4.272

Review 6.  From threat to cure: understanding of virus-induced cell death leads to highly immunogenic oncolytic influenza viruses.

Authors:  Julijan Kabiljo; Johannes Laengle; Michael Bergmann
Journal:  Cell Death Discov       Date:  2020-06-11

7.  Hepatitis A virus inhibits cellular antiviral defense mechanisms induced by double-stranded RNA.

Authors:  Kerstin Brack; Iris Berk; Thomas Magulski; Jörg Lederer; Andreas Dotzauer; Angelika Vallbracht
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

8.  Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication.

Authors:  Elizabeth Turpin; Kimberly Luke; Jeremy Jones; Terrence Tumpey; Kouacou Konan; Stacey Schultz-Cherry
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

9.  NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase.

Authors:  M Zamanian-Daryoush; T H Mogensen; J A DiDonato; B R Williams
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

10.  Isolation and characterization of noncytopathic pestivirus mutants reveals a role for nonstructural protein NS4B in viral cytopathogenicity.

Authors:  L Qu; L K McMullan; C M Rice
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103
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