Literature DB >> 8891156

Characterization of clinical isolates of beta-lactamase-negative, highly ampicillin-resistant Enterococcus faecalis.

E Cercenado1, M F Vicente, M D Díaz, C Sánchez-Carrillo, M Sánchez-Rubiales.   

Abstract

We analyzed the penicillin-binding protein (PBP) profiles of two clinical isolates of Enterococcus faecalis for which ampicillin MICs were 32 and 64 micrograms/ml. Six PBPs were detected in both isolates, demonstrating an apparently increased amount of PBP 5 and decreased penicillin binding of PBPs 1 and 6. These results suggest that ampicillin resistance in the clinical isolates of E. faecalis described could be associated with alterations in different PBPs.

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Year:  1996        PMID： 8891156      PMCID： PMC163546     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Penicillin-binding proteins and cell shape in E. coli.

Authors:  B G Spratt; A B Pardee
Journal:  Nature       Date:  1975-04-10       Impact factor: 49.962

2.  Modification of penicillin-binding proteins of penicillin-resistant mutants of different species of enterococci.

Authors:  S al-Obeid; L Gutmann; R Williamson
Journal:  J Antimicrob Chemother       Date:  1990-11       Impact factor: 5.790

3.  Antimicrobial susceptibility changes in Enterococcus faecalis following various penicillin exposure regimens.

Authors:  T L Hodges; S Zighelboim-Daum; G M Eliopoulos; C Wennersten; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

Review 4.  [Enterococcal resistance to beta-lactam and aminoglycoside antibiotics].

Authors:  J Liñares Louzao; J Ayats Ardite; T Alonso Figueres
Journal:  Rev Clin Esp       Date:  1995-10       Impact factor: 1.556

5.  Identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin.

Authors:  R Fontana; R Cerini; P Longoni; A Grossato; P Canepari
Journal:  J Bacteriol       Date:  1983-09       Impact factor: 3.490

6.  Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.

Authors:  B E Murray; B Mederski-Samaroj
Journal:  J Clin Invest       Date:  1983-09       Impact factor: 14.808

7.  High-level penicillin resistance among isolates of enterococci. Implications for treatment of enterococcal infections.

Authors:  L M Bush; J Calmon; C L Cherney; M Wendeler; P Pitsakis; J Poupard; M E Levison; C C Johnson
Journal:  Ann Intern Med       Date:  1989-04-01       Impact factor: 25.391

8.  Overproduction of a low-affinity penicillin-binding protein and high-level ampicillin resistance in Enterococcus faecium.

Authors:  R Fontana; M Aldegheri; M Ligozzi; H Lopez; A Sucari; G Satta
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

9.  Cloning, sequencing and expression in Escherichia coli of the low-affinity penicillin binding protein of Enterococcus faecalis.

Authors:  C Signoretto; M Boaretti; P Canepari
Journal:  FEMS Microbiol Lett       Date:  1994-10-15       Impact factor: 2.742
  9 in total
  2 in total

1.  Evaluation of a new system, VITEK 2, for identification and antimicrobial susceptibility testing of enterococci.

Authors:  F Garcia-Garrote; E Cercenado; E Bouza
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

2.  Enterococci: on the back burner but still simmering.

Authors:  George M Eliopoulos
Journal:  Curr Infect Dis Rep       Date:  2006-09       Impact factor: 3.725
  2 in total

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