| Literature DB >> 887929 |
B H Johnston, M A Johnson, C B Moore, J E Hearst.
Abstract
Samples of DNA which contain adducts of a new psoralen derivative, but no cross-links, have been prepared by irradiating mixtures of DNA and the derivative with single, 15-nanosecond pulses of laser light. Succeeding pulses introduce cross-links. The ability to rapidly and selectively create monoadducts and corss-links may allow the use of psoralens as probes of dynamic processes in living cells.Entities:
Mesh:
Substances:
Year: 1977 PMID: 887929 DOI: 10.1126/science.887929
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728