Literature DB >> 887929

Psoralen-DNA photoreaction: controlled production of mono- and diadducts with nanosecond ultraviolet laser pulses.

B H Johnston, M A Johnson, C B Moore, J E Hearst.   

Abstract

Samples of DNA which contain adducts of a new psoralen derivative, but no cross-links, have been prepared by irradiating mixtures of DNA and the derivative with single, 15-nanosecond pulses of laser light. Succeeding pulses introduce cross-links. The ability to rapidly and selectively create monoadducts and corss-links may allow the use of psoralens as probes of dynamic processes in living cells.

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Year:  1977        PMID: 887929     DOI: 10.1126/science.887929

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  13 in total

Review 1.  Micro-irradiation tools to visualize base excision repair and single-strand break repair.

Authors:  Natalie R Gassman; Samuel H Wilson
Journal:  DNA Repair (Amst)       Date:  2015-05-05

2.  Induction of anaerobic gene expression in Rhodobacter capsulatus is not accompanied by a local change in chromosomal supercoiling as measured by a novel assay.

Authors:  D N Cook; G A Armstrong; J E Hearst
Journal:  J Bacteriol       Date:  1989-09       Impact factor: 3.490

3.  Double stranded scission of DNA directed through sequence-specific R-loop formation.

Authors:  R Landgraf; C H Chen; D S Sigman
Journal:  Nucleic Acids Res       Date:  1995-09-11       Impact factor: 16.971

4.  Identification of the modified nucleotides produced by covalent photoaddition of hydroxymethyltrimethylpsoralen to RNA.

Authors:  J P Bachellerie; J F Thompson; M R Wegnez; J E Hearst
Journal:  Nucleic Acids Res       Date:  1981-05-11       Impact factor: 16.971

5.  Photochemical production of psoralen - DNA monoadducts capable of subsequent photocrosslinking.

Authors:  P K Chatterjee; C R Cantor
Journal:  Nucleic Acids Res       Date:  1978-10       Impact factor: 16.971

6.  Mutagenesis induced by site specifically placed 4'-hydroxymethyl-4,5',8-trimethylpsoralen adducts.

Authors:  J Piette; H B Gamper; A van de Vorst; J E Hearst
Journal:  Nucleic Acids Res       Date:  1988-11-11       Impact factor: 16.971

7.  Inactivation of Saccharomyces cells by 8-methoxypsoralen plus pulsed laser irradiation in the wavelength range 308 nm-380 nm.

Authors:  W Tuszynski; B Schaarschmidt; I Lamprecht
Journal:  Radiat Environ Biophys       Date:  1986       Impact factor: 1.925

8.  DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair.

Authors:  H P Spielmann; T J Dwyer; S S Sastry; J E Hearst; D E Wemmer
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-14       Impact factor: 11.205

9.  Viroids and prions.

Authors:  T O Diener; M P McKinley; S B Prusiner
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

10.  Termination sites of the in vitro nick-translation reaction on DNA that had photoreacted with psoralen.

Authors:  J G Piette; J E Hearst
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

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