Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Molecular cloning of two novel rab genes from human melanocytes.

Literature DB >> 8863739

Molecular cloning of two novel rab genes from human melanocytes.

D Chen¹, J Guo, T Miki, M Tachibana, W A Gahl.

Abstract

We isolated the genes of two small GTP-binding proteins of the rab family from a human melanocyte cDNA library and from melanoma cells. One gene, rab30 codes for a novel rab protein of 203 amino acids with minimal homology to previously documented GTPases. The other, rab22b, appears to be an isoform of the human homologue of canine rab22. Both rab mRNAs displayed a nearly ubiquitous pattern of expression in the various tissues examined. Rab22b and rab30 were mapped to chromosomes 18 and 11, respectively.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1996 PMID： 8863739 DOI： 10.1016/0378-1119(96)00509-4

Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688

Keyword Cloud
Cited

12 in total

1. Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.

Authors: Sudharshan Eathiraj; Xiaojing Pan; Christopher Ritacco; David G Lambright
Journal: Nature Date: 2005-07-21 Impact factor: 49.962

2. Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31.

Authors: Hiroaki Kajiho; Kyoko Sakurai; Tomohiro Minoda; Manabu Yoshikawa; Satoshi Nakagawa; Shinichi Fukushima; Kenji Kontani; Toshiaki Katada
Journal: J Biol Chem Date: 2011-05-17 Impact factor: 5.157

3. Microarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer.

Authors: Haitao Zhang; Yan Dong; Hongjuan Zhao; James D Brooks; Lesleyann Hawthorn; Norma Nowak; James R Marshall; Allen C Gao; Clement Ip
Journal: Cancer Genomics Proteomics Date: 2005-04 Impact factor: 4.069

Review 4. Are Rab proteins the link between Golgi organization and membrane trafficking?

Authors: Shijie Liu; Brian Storrie
Journal: Cell Mol Life Sci Date: 2012-05-13 Impact factor: 9.261

5. Engagement of the small GTPase Rab31 protein and its effector, early endosome antigen 1, is important for trafficking of the ligand-bound epidermal growth factor receptor from the early to the late endosome.

Authors: Christelle En Lin Chua; Bor Luen Tang
Journal: J Biol Chem Date: 2014-03-18 Impact factor: 5.157

6. Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling.

Authors: Ingo Nindl; Chantip Dang; Tobias Forschner; Ralf J Kuban; Thomas Meyer; Wolfram Sterry; Eggert Stockfleth
Journal: Mol Cancer Date: 2006-08-08 Impact factor: 27.401

Molecular cloning of two novel rab genes from human melanocytes.

1. Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.

2. Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31.

3. Microarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer.

Review 4. Are Rab proteins the link between Golgi organization and membrane trafficking?

5. Engagement of the small GTPase Rab31 protein and its effector, early endosome antigen 1, is important for trafficking of the ligand-bound epidermal growth factor receptor from the early to the late endosome.

6. Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling.

Review 7. The role of the small GTPase Rab31 in cancer.

8. RAB-6.1 and RAB-6.2 Promote Retrograde Transport in C. elegans.

9. Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells.

10. Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes.