Literature DB >> 8862747

Effect of vanadium compounds on acid phosphatase activity.

C M Vescina1, V C Sálice, A M Cortizo, S B Etcheverry.   

Abstract

The direct effect of different vanadium compounds on acid phosphatase (ACP) activity was investigated. Vanadate and vanadyl but not pervanadate inhibited the wheat germ ACP activity. These vanadium derivatives did not alter the fibroblast Swiss 3T3 soluble fraction ACP activity. Using inhibitors of tyrosine phosphatases (PTPases), the wheat germ ACP was partially characterized as a PTPase. This study suggests that the inhibitory ability of different vanadium derivatives to modulate ACP activity seems to depend on the geometry around the vanadium atom more than on the oxidation state. Our results indicate a correlation between the PTPase activity and the sensitivity to vanadate and vanadyl cation.

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Year:  1996        PMID: 8862747     DOI: 10.1007/BF02784554

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  14 in total

1.  Mitogens regulate the production of insulin-like growth factor-binding protein by Swiss 3T3 cells.

Authors:  A N Corps; K D Brown
Journal:  Endocrinology       Date:  1991-02       Impact factor: 4.736

2.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

Review 3.  Phosphotyrosyl protein phosphatases.

Authors:  K H Lau; J R Farley; D J Baylink
Journal:  Biochem J       Date:  1989-01-01       Impact factor: 3.857

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Authors:  N K Tonks; C D Diltz; E H Fischer
Journal:  J Biol Chem       Date:  1988-05-15       Impact factor: 5.157

5.  Identification, purification, and characterization of phosphotyrosine-specific protein phosphatases from cultured chicken embryo fibroblasts.

Authors:  R L Nelson; P E Branton
Journal:  Mol Cell Biol       Date:  1984-06       Impact factor: 4.272

6.  Stimulation of insulin-like growth factor II receptor binding and insulin receptor kinase activity in rat adipocytes. Effects of vanadate and H2O2.

Authors:  S Kadota; I G Fantus; G Deragon; H J Guyda; B I Posner
Journal:  J Biol Chem       Date:  1987-06-15       Impact factor: 5.157

7.  Effects of vanadate on protein kinases in rat hepatocytes.

Authors:  C Villar-Palasi; J J Guinovart; A M Gómez-Foix; J E Rodriguez-Gil; F Bosch
Journal:  Biochem J       Date:  1989-09-01       Impact factor: 3.857

8.  Vanadium compounds. Their action on alkaline phosphatase activity.

Authors:  A M Cortizo; V C Salice; S B Etcheverry
Journal:  Biol Trace Elem Res       Date:  1994-06       Impact factor: 3.738

9.  Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle.

Authors:  L C Cantley; L Josephson; R Warner; M Yanagisawa; C Lechene; G Guidotti
Journal:  J Biol Chem       Date:  1977-11-10       Impact factor: 5.157

10.  Vanadium derivatives act as growth factor--mimetic compounds upon differentiation and proliferation of osteoblast-like UMR106 cells.

Authors:  A M Cortizo; S B Etcheverry
Journal:  Mol Cell Biochem       Date:  1995-04-26       Impact factor: 3.396

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  1 in total

Review 1.  Vanadium in Biological Action: Chemical, Pharmacological Aspects, and Metabolic Implications in Diabetes Mellitus.

Authors:  Samuel Treviño; Alfonso Díaz; Eduardo Sánchez-Lara; Brenda L Sanchez-Gaytan; Jose Manuel Perez-Aguilar; Enrique González-Vergara
Journal:  Biol Trace Elem Res       Date:  2018-10-22       Impact factor: 3.738

  1 in total

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