Literature DB >> 884872

The occurrence of 2-hydroxyisovaleric acid in patients with lactic acidosis and ketoacidosis.

S Landaas, C Jakobs.   

Abstract

Examination of urine samples by capillary column gas chromatography and mass spectrometry showed the presence of 2-hydroxyisovaleric acid together with trace amounts of the three branched-chain 2-keto acids in five patients with lactic and ketoacidosis. None of these compounds was detected in urine from healthy controls.

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Year:  1977        PMID： 884872     DOI： 10.1016/0009-8981(77)90082-1

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  8 in total

1.  3-Hydroxyglutarate excretion is increased in ketotic patients: implications for glutaryl-CoA dehydrogenase deficiency testing.

Authors:  J Pitt; K Carpenter; B Wilcken; A Boneh
Journal:  J Inherit Metab Dis       Date:  2002-05       Impact factor: 4.982

2.  Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit.

Authors:  Beata Mickiewicz; Patrick Tam; Craig N Jenne; Caroline Leger; Josee Wong; Brent W Winston; Christopher Doig; Paul Kubes; Hans J Vogel
Journal:  Crit Care       Date:  2015-01-15       Impact factor: 9.097

3.  Identification of human D lactate dehydrogenase deficiency.

Authors:  Glen R Monroe; Albertien M van Eerde; Federico Tessadori; Karen J Duran; Sanne M C Savelberg; Johanna C van Alfen; Paulien A Terhal; Saskia N van der Crabben; Klaske D Lichtenbelt; Sabine A Fuchs; Johan Gerrits; Markus J van Roosmalen; Koen L van Gassen; Mirjam van Aalderen; Bart G Koot; Marlies Oostendorp; Marinus Duran; Gepke Visser; Tom J de Koning; Francesco Calì; Paolo Bosco; Karin Geleijns; Monique G M de Sain-van der Velden; Nine V Knoers; Jeroen Bakkers; Nanda M Verhoeven-Duif; Gijs van Haaften; Judith J Jans
Journal:  Nat Commun       Date:  2019-04-01       Impact factor: 14.919

4.  Metabolic modulation predicts heart failure tests performance.

Authors:  Daniel Contaifer; Leo F Buckley; George Wohlford; Naren G Kumar; Joshua M Morriss; Asanga D Ranasinghe; Salvatore Carbone; Justin M Canada; Cory Trankle; Antonio Abbate; Benjamin W Van Tassell; Dayanjan S Wijesinghe
Journal:  PLoS One       Date:  2019-06-20       Impact factor: 3.240

5.  Metabolomic studies as a tool for determining the post-mortem interval (PMI) in stillborn calves.

Authors:  Paulina Jawor; Adam Ząbek; Wojciech Wojtowicz; Dawid Król; Tadeusz Stefaniak; Piotr Młynarz
Journal:  BMC Vet Res       Date:  2019-06-07       Impact factor: 2.741

6.  Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague-Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles.

Authors:  Richard A Forsgård; Vannina G Marrachelli; Jere Lindén; Rafael Frias; Maria Carmen Collado; Riitta Korpela; Daniel Monleon; Thomas Spillmann; Pia Österlund
Journal:  Transl Oncol       Date:  2019-06-06       Impact factor: 4.243

7.  Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder.

Authors:  Jingshu Xu; Paul Begley; Stephanie J Church; Stefano Patassini; Katherine A Hollywood; Mia Jüllig; Maurice A Curtis; Henry J Waldvogel; Richard L M Faull; Richard D Unwin; Garth J S Cooper
Journal:  Biochim Biophys Acta       Date:  2016-03-05

Review 8.  Ascites modulates cancer cell behavior, contributing to tumor heterogeneity in ovarian cancer.

Authors:  Soochi Kim; Boyun Kim; Yong Sang Song
Journal:  Cancer Sci       Date:  2016-08-16       Impact factor: 6.716
  8 in total

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