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Literature DB >> 88405

Correlated inhibition of ribosomal RNA synthesis and silver staining by actinomycin D.

Abstract

Preferential inhibition of the synthesis of ribosomal RNA by low doses of actinomycin D was used to investigate the quantitative relationship between the intensity of silver staining of nucleoli and the rate of RNA-synthesis. The two parameters were found to be strongly correlated in human diploid fibroblasts.

Entities: Chemical Species

Mesh：

Substances：

Year: 1979 PMID： 88405 DOI： 10.1007/BF00321025

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

12 in total

1. THE EFFECT OF ACTINOMYCIN D ON THE FINE STRUCTURE OF THE NUCLEOLUS.

Authors: G I SCHOEFL
Journal: J Ultrastruct Res Date: 1964-04

2. NUCLEOLAR "CAPS" PRODUCED BY ACTINOMYCIN D.

Authors: R C REYNOLDS; P O MONTGOMERY; B HUGHES
Journal: Cancer Res Date: 1964-08 Impact factor: 12.701

3. Expression of human and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids.

Authors: O J Miller; D A Miller; V G Dev; R Tantravahi; C M Croce
Journal: Proc Natl Acad Sci U S A Date: 1976-12 Impact factor: 11.205

Review 4. The nucleolar structure.

Authors: S Ghosh
Journal: Int Rev Cytol Date: 1976

5. Activation of mouse ribosomal RNA genes at the 2-cell stage.

Authors: W Engel; M T Zenzes; M Schmid
Journal: Hum Genet Date: 1977-08-31 Impact factor: 4.132

Review 6. Structure and synthesis of ribosomal RNA.

Authors: G Attardi; F Amaldi
Journal: Annu Rev Biochem Date: 1970 Impact factor: 23.643

7. Early alterations in amino acid pools and protein synthesis of diploid fibroblasts stimulated to synthesize DNA by addition of serum.

Authors: F Wiebel; R Baserga
Journal: J Cell Physiol Date: 1969-10 Impact factor: 6.384

8. Onset of nucleolus organizer activity in early mouse embryogenesis and evidence for its regulation.

Authors: I Hansmann; J Gebauer; L Bihl; T Grimm
Journal: Exp Cell Res Date: 1978-07 Impact factor: 3.905

9. The nature of the Ag-staining of nucleolus organizer regions. Electron- and light-microscopic studies on human cells in interphase, mitosis, and meiosis.

Authors: H G Schwarzacher; A V Mikelsaar; W Schnedl
Journal: Cytogenet Cell Genet Date: 1978

10. Evidence for postmeiotic expression of ribosomal RNA genes during male gametogenesis.

Authors: M Schmid; F J Hofgärtner; M T Zenzes; W Engel
Journal: Hum Genet Date: 1977-10-14 Impact factor: 4.132

16 in total

1. Nucleolus organizer regions in human lymphocytes as studied with premature chromosome condensation.

Authors: F Wachtler; C Roubicek; A Schedle; W Mosgöller; G Bretis; H G Schwarzacher
Journal: Hum Genet Date: 1990-02 Impact factor: 4.132

2. Argyrophilic nucleolar organiser region (AgNOR) staining in normal bone marrow cells.

Authors: E P Nikicicz; D H Norback
Journal: J Clin Pathol Date: 1990-09 Impact factor: 3.411

3. Ultrastructural localization of Ag-NOR stained proteins in the nucleolus during the cell cycle and in other nucleolar structures.

Authors: D Hernandez-Verdun; J Hubert; C A Bourgeois; M Bouteille
Journal: Chromosoma Date: 1980 Impact factor: 4.316

Correlated inhibition of ribosomal RNA synthesis and silver staining by actinomycin D.

1. THE EFFECT OF ACTINOMYCIN D ON THE FINE STRUCTURE OF THE NUCLEOLUS.

2. NUCLEOLAR "CAPS" PRODUCED BY ACTINOMYCIN D.

3. Expression of human and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids.

Review 4. The nucleolar structure.

5. Activation of mouse ribosomal RNA genes at the 2-cell stage.

Review 6. Structure and synthesis of ribosomal RNA.

7. Early alterations in amino acid pools and protein synthesis of diploid fibroblasts stimulated to synthesize DNA by addition of serum.

8. Onset of nucleolus organizer activity in early mouse embryogenesis and evidence for its regulation.

9. The nature of the Ag-staining of nucleolus organizer regions. Electron- and light-microscopic studies on human cells in interphase, mitosis, and meiosis.

10. Evidence for postmeiotic expression of ribosomal RNA genes during male gametogenesis.

1. Nucleolus organizer regions in human lymphocytes as studied with premature chromosome condensation.

2. Argyrophilic nucleolar organiser region (AgNOR) staining in normal bone marrow cells.

3. Ultrastructural localization of Ag-NOR stained proteins in the nucleolus during the cell cycle and in other nucleolar structures.

4. Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine.

5. Reprogramming of rye rDNA in triticale during microsporogenesis.

6. Silver staining of nucleolus organizer regions during human spermatogenesis.

7. Specific silver staining of experimentally undercondensed chromosome regions.

8. Observations on the dynamics of argyrophilic nucleolar material in the nuclei of mice spermatids.

9. Visualization of Ag-NOR proteins on nucleolar transcriptional units in molecular spreads.

10. Increased silver stainability of metaphase chromosomes from rat hepatocytes during in vivo hepatocarcinogenesis.