Literature DB >> 883965

Effects of acetoacetate administration on glucose metabolism in mammary gland of fed lactating rats.

A M Robinson, D H Williamson.   

Abstract

Administration of acetoactate to fed lactating rats rapidly decreases glucose uptake by the mammary gland, and causes an output of pyruvate, whereas lactate uptake remains unchanged. Similar changes, though not identical, occur in starved lactating rats, which suggests that the increased acetoacetate concentration in this situation may be one of the factors responsible for the alterations in glucose metabolism.

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Year:  1977        PMID： 883965      PMCID： PMC1164855          DOI： 10.1042/bj1640749

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  10 in total

1.  Enzymic determination of D(-)-beta-hydroxybutyric acid and acetoacetic acid in blood.

Authors:  D H WILLIAMSON; J MELLANBY; H A KREBS
Journal:  Biochem J       Date:  1962-01       Impact factor: 3.857

2.  [A simple technic for extremely rapid freezing of large pieces of tissue].

Authors:  A WOLLENBERGER; O RISTAU; G SCHOFFA
Journal:  Pflugers Arch Gesamte Physiol Menschen Tiere       Date:  1960

3.  [On the metabolite content and the metabolite concentration in the liver of the rat].

Authors:  H J HOHORST; F H KREUTZ; T BUECHER
Journal:  Biochem Z       Date:  1959

4.  Regulation of mammalian pyruvate dehydrogenase.

Authors:  R M Denton; P J Randle; B J Bridges; R H Cooper; A L Kerbey; H T Pask; D L Severson; D Stansbie; S Whitehouse
Journal:  Mol Cell Biochem       Date:  1975-10-31       Impact factor: 3.396

5.  Measurements of substrate uptake by mammary gland of the rat.

Authors:  R A Hawkins; D H Williamson
Journal:  Biochem J       Date:  1972-10       Impact factor: 3.857

6.  Activity of pyruvate dehydrogenase complex in the mammary gland of normal and diabetic rats.

Authors:  K F Kankel; H Reinauer
Journal:  Diabetologia       Date:  1976-05       Impact factor: 10.122

7.  The effect of acetoacetate on plasma insulin concentration.

Authors:  R A Hawkins; K G Alberti; C R Houghton; D H Williamson; H A Krebs
Journal:  Biochem J       Date:  1971-11       Impact factor: 3.857

8.  Comparison of glucose metabolism in the lactating mammary gland of the rat in vivo and in vitro. Effects of starvation, prolactin or insulin deficiency.

Authors:  A M Robinson; D H Williamson
Journal:  Biochem J       Date:  1977-04-15       Impact factor: 3.857

9.  Regulation of triglyceride synthesis in the parturient guinea-pig mammary gland.

Authors:  N J Kuhn
Journal:  Biochem J       Date:  1967-10       Impact factor: 3.857

10.  Interactions of glucose, acetoacetate and insulin in mammary-gland slices of lactating rats.

Authors:  D H Williamson; S R McKeown; V Ilic
Journal:  Biochem J       Date:  1975-08       Impact factor: 3.857
  10 in total
  11 in total

1.  Dermot Hedley (Derek) Williamson (1929-1998).

Authors:  T H Da Costa; R D Evans
Journal:  J Mammary Gland Biol Neoplasia       Date:  2001-04       Impact factor: 2.673

2.  Utlization of D-3-hydroxy[3-14C]butyrate for lipogenesis in vivo in lactating rat mammary gland.

Authors:  A M Robinson; D H Williamson
Journal:  Biochem J       Date:  1978-11-15       Impact factor: 3.857

3.  Control of glucose metabolism in isolated acini of the lactating mamary gland of the rat. Effects of oleate on glucose utilization and lipogenesis.

Authors:  A M Robinson; D H Williamson
Journal:  Biochem J       Date:  1978-03-15       Impact factor: 3.857

4.  Monosaccharide transport in the mammary gland of the intact lactating rat.

Authors:  L C Threadgold; N J Kuhn
Journal:  Biochem J       Date:  1984-02-15       Impact factor: 3.857

5.  Effect of starvation and refeeding on amino acid uptake by mammary gland of the lactating rat. Role of ketone bodies.

Authors:  J R Viña; I R Puertes; J B Montoro; J Viña
Journal:  Biochem J       Date:  1983-11-15       Impact factor: 3.857

6.  Rapid inhibition by intragastric triolein of the re-activation of glucose utilization and lipogenesis in the mammary gland during the starved-refed transition in lactating rats. Evidence for a direct effect of oral lipid on mammary tissue.

Authors:  S W Mercer; D H Williamson
Journal:  Biochem J       Date:  1988-02-15       Impact factor: 3.857

7.  Comparison of the flux of carbon to hepatic glycogen deposition and fatty acid and cholesterol synthesis on refeeding rats fed ad libitum or meal-fed rats with a chow-diet meal.

Authors:  F V Pallardo; D H Williamson
Journal:  Biochem J       Date:  1989-01-15       Impact factor: 3.857

8.  Effects of starvation and exercise on concentrations of citrate, hexose phosphates and glycogen in skeletal muscle and heart. Evidence for selective operation of the glucose-fatty acid cycle.

Authors:  A Zorzano; T W Balon; L J Brady; P Rivera; L P Garetto; J C Young; M N Goodman; N B Ruderman
Journal:  Biochem J       Date:  1985-12-01       Impact factor: 3.857

9.  Control of glucose metabolism in isolated acini of the lactating mammary gland of the rat. The ability of glycerol to mimic some of the effects of insulin.

Authors:  A M Robinson; D H Williamson
Journal:  Biochem J       Date:  1977-12-15       Impact factor: 3.857

10.  Diurnal variation and response to food withdrawal of lactose synthesis in lactating rats.

Authors:  D T Carrick; N J Kuhn
Journal:  Biochem J       Date:  1978-07-15       Impact factor: 3.857
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