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Literature DB >> 6056624

Regulation of triglyceride synthesis in the parturient guinea-pig mammary gland.

Abstract

1. The specific activity of the enzyme palmitoyl-CoA-l-glycerol 3-phosphate palmitoyltransferase (EC 2.3.1.15) in the mammary tissue of guinea pigs has been shown to increase 37-fold at parturition. 2. Increases also occur in tissue concentrations of glycerol 3-phosphate, CoA and free fatty acid, but not in that of acid-insoluble CoA. 3. The isolation and fatty acid composition of plasma triglyceride and of mammary-tissue free fatty acid, diglyceride and triglyceride are described. 4. The findings are discussed in relation to the regulation of milk fat synthesis.

Entities: Chemical Species

Mesh：

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Year: 1967 PMID： 6056624 PMCID： PMC1198293 DOI： 10.1042/bj1050225

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

28 in total

1. CHANGES IN THE LIPOLYTIC ACTIVITY OF THE GUINEA PIG MAMMARY GLAND AT PARTURITION.

Authors: D S ROBINSON
Journal: J Lipid Res Date: 1963-01 Impact factor: 5.922

2. ALPHA-GLYCEROPHOSPHATE AS REGULATORY FACTOR IN FATTY ACID ESTERIFICATION.

Authors: R TZUR; E TAL; B SHAPIRO
Journal: Biochim Biophys Acta Date: 1964-02-24

3. THE UPTAKE FROM THE BLOOD OF TRIGLYCERIDE FATTY ACIDS OF CHYLOMICRA AND LOW-DENSITY LIPOPROTEINS BY THE MAMMARY GLAND OF THE GOAT.

Authors: J M BARRY; W BARTLEY; J L LINZELL; D S ROBINSON
Journal: Biochem J Date: 1963-10 Impact factor: 3.857

5. Control of glucose metabolism in isolated acini of the lactating mammary gland of the rat. The ability of glycerol to mimic some of the effects of insulin.

Authors: A M Robinson; D H Williamson
Journal: Biochem J Date: 1977-12-15 Impact factor: 3.857

6. Esterification of glycerol 3-phosphate in lactating guinea-pig mammary gland.

Authors: N J Kuhn
Journal: Biochem J Date: 1967-10 Impact factor: 3.857

6 in total

Regulation of triglyceride synthesis in the parturient guinea-pig mammary gland.

1. CHANGES IN THE LIPOLYTIC ACTIVITY OF THE GUINEA PIG MAMMARY GLAND AT PARTURITION.

2. ALPHA-GLYCEROPHOSPHATE AS REGULATORY FACTOR IN FATTY ACID ESTERIFICATION.

3. THE UPTAKE FROM THE BLOOD OF TRIGLYCERIDE FATTY ACIDS OF CHYLOMICRA AND LOW-DENSITY LIPOPROTEINS BY THE MAMMARY GLAND OF THE GOAT.

4. Transport of fatty acids.

5. Separation of lipid classes by chromatography on Florisil.

6. Microdetermination of long-chain fatty acids in plasma and tissues.

7. Biosynthesis of milk-fat in the rabbit from acetate and glucose; the mode of conversion of carbohydrate into fat.

8. Enzymatic synthesis of citric acid. II. Crystalline condensing enzyme.

9. The uptake of doubly labeled chylomicrons by guinea pig mammary gland and liver.

10. Presence of glycerokinase in guinea pig mammary gland and the incorporation of glycerol into glycerides.

1. Effects of acetoacetate administration on glucose metabolism in mammary gland of fed lactating rats.

2. Fatty acid specificity of glyceride synthesis by homogenates of bovine mammary tissue.

3. Lactogenesis in the rat. Changes in metabolic parameters at parturition.

4. Triglyceride synthesis by the small-intestinal epithelium of the pig, sheep and chicken.

5. Control of glucose metabolism in isolated acini of the lactating mammary gland of the rat. The ability of glycerol to mimic some of the effects of insulin.

6. Esterification of glycerol 3-phosphate in lactating guinea-pig mammary gland.