Literature DB >> 8834899

Some repair-deficient mutants of Dictyostelium discoideum display enhanced susceptibilities to bleomycin.

R A Deering1, R B Guyer, L Stevens, T E Watson-Thais.   

Abstract

Dictyostelium discoideum, a soil eukaryote, is highly resistant to DNA-damaging agents; repair mutants are more susceptible. Susceptibility to bleomycin, produced by Streptomyces verticillus, is greater for mutants which are susceptible to other agents than for resistant strains. The high potential for DNA repair may result from the need to cope with chemicals produced by other soil microorganisms.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8834899      PMCID： PMC163135     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

1.  Establishment of a transient expression system for Dictyostelium discoideum.

Authors:  P K Howard; K G Ahern; R A Firtel
Journal:  Nucleic Acids Res       Date:  1988-03-25       Impact factor: 16.971

2.  Biochemical evidence for two different mechanisms for bleomycin-induced cell killing.

Authors:  A J Giaccia; J Shieh; A Cholon; J M Brown
Journal:  Mutat Res       Date:  1991-06       Impact factor: 2.433

3.  Bleomycin resistance as a selectable marker for transformation of the eukaryote, Dictyostelium discoideum.

Authors:  A C Chang; R M Hall; K L Williams
Journal:  Gene       Date:  1991-10-30       Impact factor: 3.688

4.  Structure of bleomycin-induced DNA double-strand breaks: predominance of blunt ends and single-base 5' extensions.

Authors:  L F Povirk; Y H Han; R J Steighner
Journal:  Biochemistry       Date:  1989-07-11       Impact factor: 3.162

5.  Interactions between radiation-sensitive mutations in double-mutant haploids of Dictyostelium discoideum.

Authors:  D L Welker; R A Deering
Journal:  Mol Gen Genet       Date:  1979-01-02

6.  DNA double-strand breaks and alkali-labile bonds produced by bleomycin.

Authors:  L F Povirk; W Wübter; W Köhnlein; F Hutchinson
Journal:  Nucleic Acids Res       Date:  1977-10       Impact factor: 16.971

7.  Tn5-mediated bleomycin resistance in Escherichia coli requires the expression of host genes.

Authors:  M Blot; J Heitman; W Arber
Journal:  Mol Microbiol       Date:  1993-06       Impact factor: 3.501

Review 8.  Mechanisms of multidrug resistance in cancer treatment.

Authors:  A L Harris; D Hochhauser
Journal:  Acta Oncol       Date:  1992       Impact factor: 4.089

9.  Mutations affecting sensitivity of the cellular slime mold Dictyostelium discoideum to DNA-damaging agents.

Authors:  C E Bronner; D L Welker; R A Deering
Journal:  Mutat Res       Date:  1992-09       Impact factor: 2.433

10.  Effect of apurinic/apyrimidinic endonucleases and polyamines on DNA treated with bleomycin and neocarzinostatin: specific formation and cleavage of closely opposed lesions in complementary strands.

Authors:  L F Povirk; C W Houlgrave
Journal:  Biochemistry       Date:  1988-05-17       Impact factor: 3.162
View more
  3 in total

1.  An unusually low microsatellite mutation rate in Dictyostelium discoideum, an organism with unusually abundant microsatellites.

Authors:  Ryan McConnell; Sara Middlemist; Clea Scala; Joan E Strassmann; David C Queller
Journal:  Genetics       Date:  2007-10-18       Impact factor: 4.562

Review 2.  The role of ADP-ribosylation in regulating DNA double-strand break repair.

Authors:  Catherine J Pears; C Anne-Marie Couto; Hong-Yu Wang; Christine Borer; Rhian Kiely; Nicholas D Lakin
Journal:  Cell Cycle       Date:  2012-01-01       Impact factor: 4.534

3.  Whole genome sequencing of mutation accumulation lines reveals a low mutation rate in the social amoeba Dictyostelium discoideum.

Authors:  Gerda Saxer; Paul Havlak; Sara A Fox; Michael A Quance; Sharu Gupta; Yuriy Fofanov; Joan E Strassmann; David C Queller
Journal:  PLoS One       Date:  2012-10-08       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.