Literature DB >> 8832335

Thermogenic responses to high-energy phosphate contents and/or hindlimb suspension in rats.

T Wakatsuki1, F Hirata, H Ohno, M Yamamoto, Y Sato, Y Ohira.   

Abstract

Effects of chronic depletion of high-energy phosphate compounds by feeding beta-guanidinopropionic acid (beta-GPA) with or without hindlimb suspension (HS) on body temperature were studied in rats. Lower rectal and skin temperatures were observed in rats after 10 d of HS. Suspension-related enlargement of the interscapular brown adipose tissue (BAT), associated with adrenal hypertrophy, was seen. Feeding beta-GPA also caused a hypothermia and BAT enlargement. It is suggested that the hypothermic response to HS may be due to decreased contractile activity and metabolic rate in skeletal muscles, associated with stress. It is also speculated that the changes in the thermogenesis in rats fed beta-GPA might be related to a stimulated ATP synthesis with sacrificed heat production, but not associated with stress.

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Year:  1996        PMID： 8832335     DOI： 10.2170/jjphysiol.46.171

Source DB:  PubMed          Journal:  Jpn J Physiol        ISSN： 0021-521X


  8 in total

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Journal:  J Physiol Sci       Date:  2015-04-08       Impact factor: 2.781

Review 2.  Creatine metabolism: energy homeostasis, immunity and cancer biology.

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3.  Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

Authors:  Lawrence Kazak; Edward T Chouchani; Gina Z Lu; Mark P Jedrychowski; Curtis J Bare; Amir I Mina; Manju Kumari; Song Zhang; Ivan Vuckovic; Dina Laznik-Bogoslavski; Petras Dzeja; Alexander S Banks; Evan D Rosen; Bruce M Spiegelman
Journal:  Cell Metab       Date:  2017-08-24       Impact factor: 27.287

4.  A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.

Authors:  Lawrence Kazak; Edward T Chouchani; Mark P Jedrychowski; Brian K Erickson; Kosaku Shinoda; Paul Cohen; Ramalingam Vetrivelan; Gina Z Lu; Dina Laznik-Bogoslavski; Sebastian C Hasenfuss; Shingo Kajimura; Steve P Gygi; Bruce M Spiegelman
Journal:  Cell       Date:  2015-10-22       Impact factor: 41.582

5.  Differential response of adipose tissue gene and protein expressions to 4- and 8-week administration of β-guanidinopropionic acid in mice.

Authors:  Hisashi Kato; Shinya Masuda; Tomotaka Ohira; Luna Ohira; Hisashi Takakura; Yoshinobu Ohira; Tetsuya Izawa
Journal:  Physiol Rep       Date:  2018-03

Review 6.  Current Evidence and Possible Future Applications of Creatine Supplementation for Older Adults.

Authors:  Darren G Candow; Scott C Forbes; Ben Kirk; Gustavo Duque
Journal:  Nutrients       Date:  2021-02-26       Impact factor: 5.717

Review 7.  The effect of the creatine analogue beta-guanidinopropionic acid on energy metabolism: a systematic review.

Authors:  Inge Oudman; Joseph F Clark; Lizzy M Brewster
Journal:  PLoS One       Date:  2013-01-09       Impact factor: 3.240

Review 8.  UCP1 Dependent and Independent Thermogenesis in Brown and Beige Adipocytes.

Authors:  Kenji Ikeda; Tetsuya Yamada
Journal:  Front Endocrinol (Lausanne)       Date:  2020-07-28       Impact factor: 5.555
  8 in total

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