Literature DB >> 8825545

Study design in clinical research: sample size estimation and power analysis.

J Lerman1.   

Abstract

The purpose of this review is to describe the statistical methods available to determine sample size and power analysis in clinical trials. The information was obtained from standard textbooks and personal experience. Equations are provided for the calculations and suggestions are made for the use of power tables. It is concluded that sample size calculations and power analysis can be performed with the information provided and that the validity of clinical investigation would be improved by greater use of such analyses.

Mesh:

Year:  1996        PMID: 8825545     DOI: 10.1007/BF03011261

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  4 in total

1.  The statistical power of abnormal-social psychological research: a review.

Authors:  J COHEN
Journal:  J Abnorm Soc Psychol       Date:  1962-09

2.  An exploratory study of statistical assessment of papers published in the British Medical Journal.

Authors:  M J Gardner; J Bond
Journal:  JAMA       Date:  1990-03-09       Impact factor: 56.272

3.  The importance of beta, the type II error and sample size in the design and interpretation of the randomized control trial. Survey of 71 "negative" trials.

Authors:  J A Freiman; T C Chalmers; H Smith; R R Kuebler
Journal:  N Engl J Med       Date:  1978-09-28       Impact factor: 91.245

4.  Experimental design and statistical analysis.

Authors:  P F Moodie; D B Craig
Journal:  Can Anaesth Soc J       Date:  1986-01
  4 in total
  23 in total

1.  Use of normative distribution of gray to white matter ratio in orthogonal planes in human brain studies and computer-assisted neuroradiology.

Authors:  Wieslaw L Nowinski; Varsha Gupta; Wai Yen Chan; Yih-Yian Sitoh; Kang Sim
Journal:  Int J Comput Assist Radiol Surg       Date:  2010-12-16       Impact factor: 2.924

2.  Sample size matters: a guide for surgeons.

Authors:  Ulrich Guller; Daniel Oertli
Journal:  World J Surg       Date:  2005-05       Impact factor: 3.352

3.  Effects of graded levels of exercise on ipsilateral and contralateral post-exercise resting rectus femoris mechanomyography.

Authors:  William P S McKay; Perry Jacobson; Philip D Chilibeck; Brian L F Daku
Journal:  Eur J Appl Physiol       Date:  2006-10-06       Impact factor: 3.078

4.  Gene expression profiling in the rhesus macaque: methodology, annotation and data interpretation.

Authors:  Nigel C Noriega; Steven G Kohama; Henryk F Urbanski
Journal:  Methods       Date:  2009-05-23       Impact factor: 3.608

5.  [Spinal anaesthesia in day-case surgery. Optimisation of procedures].

Authors:  G Rätsch; H Niebergall; L Hauenstein; A Reber
Journal:  Anaesthesist       Date:  2007-04       Impact factor: 1.041

6.  Association of genetic and non-genetic risk factors with the development of prostate cancer in Malaysian men.

Authors:  Khamsigan Munretnam; Livy Alex; Nurul Hanis Ramzi; Jagdish Kaur Chahil; I S Kavitha; Nikman Adli Nor Hashim; Say Hean Lye; Sharmila Velapasamy; Lian Wee Ler
Journal:  Mol Biol Rep       Date:  2014-01-18       Impact factor: 2.316

7.  Changes in the first postoperative night bispectral index of patients after thyroidectomy with different types of primary anesthetic management: a randomized controlled trial.

Authors:  Wen-Fei Tan; Zhi-Lin Wang; Hong Ma; Feng Jin; Huang-Wei Lu
Journal:  J Clin Monit Comput       Date:  2017-01-12       Impact factor: 2.502

8.  Comparison of dexamethasone with ondansetron or haloperidol for prevention of patient-controlled analgesia-related postoperative nausea and vomiting: a randomized clinical trial.

Authors:  Po-Kai Wang; Pei-Jiuan Tsay; Chia-Chun Huang; Hsien-Yong Lai; Pei-Chin Lin; Shen-Jer Huang; Yi Lee
Journal:  World J Surg       Date:  2012-04       Impact factor: 3.352

9.  Effects of ultrasound-guided stellate-ganglion block on sleep and regional cerebral oxygen saturation in patients undergoing breast cancer surgery: a randomized, controlled, double-blinded trial.

Authors:  Feng Jin; Xiao-Qian Li; Wen-Fei Tan; Hong Ma; Bo Fang; A-Yong Tian; Huang-Wei Lu
Journal:  J Clin Monit Comput       Date:  2017-10-17       Impact factor: 2.502

10.  No Superiority of Granisetron Over Metoclopramide in Prevention of Post-operative Nausea and Vomiting: A Randomized Clinical Trial.

Authors:  Ashraf Aleyasin; Alireza Hayatshahi; Elham Saffarieh; Hassan Torkamandi; Marzieh Aghahosseini; Somayeh Hanafi; Fariborz Sadeghi; Mohammadreza Javadi
Journal:  J Obstet Gynaecol India       Date:  2013-10-08
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