| Literature DB >> 881461 |
K M Smith, R N Johnson, B T Kho.
Abstract
A description is given of a gas chromatographic method for the determination of hydralizine in various tablet formulations based on the quantitative reaction of hydralazine with 2,4-pentanedione to yield 1-(3,5-dimethylpyrazole)phthalazine. The stable hydralazine derivative formed is extracted from aqueous solution and chromatographed resulting in a precise and specific determination of hydralazine which correlates well with the U.S.P. XIX titrimetric procedure.Entities:
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Year: 1977 PMID： 881461 DOI： 10.1016/s0021-9673(00)81365-5
Source DB: PubMed Journal: J Chromatogr