Literature DB >> 7067722

Studies on the metabolism of cadralazine in rat.

L Simonotti, M Zanol, F Parravicini, G Pifferi.   

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Year:  1982        PMID： 7067722     DOI： 10.1007/BF03189541

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN： 0378-7966            Impact factor:   2.441


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  8 in total

1.  Determination of hydralazine and its metabolites by gas chromatography-mass spectrometry.

Authors:  K D Haegele; H B Skrdlant; N W Robie; D Lalka; J L McNay
Journal:  J Chromatogr       Date:  1976-11-03

2.  Metabolism of budralazine, a new antihypertensive agent. II. Metabolic pathways of budralazine in rats.

Authors:  R Moroi; K Ono; T Saito; T Akimoto; M Sano
Journal:  Chem Pharm Bull (Tokyo)       Date:  1977-04       Impact factor: 1.645

3.  Determination of hydralazine in tablets by gas chromatography.

Authors:  K M Smith; R N Johnson; B T Kho
Journal:  J Chromatogr       Date:  1977-07-21

4.  [Studied on 14C-labelled N1-carboethoxy-N2-hydrazinophthalazine hydrochloride (Apiracohl). I. Synthesis of labelled compound and metabolism in rats (author's transl)].

Authors:  A Ishii; T Deguchi; H Takahira
Journal:  Yakugaku Zasshi       Date:  1973-10       Impact factor: 0.302

5.  Antihypertensive efficacy of a new long acting hydralazine like vasodilator, ISF 2469 in combination with a betablocker and a diuretic.

Authors:  P van Brummelen; F R Bühler; W Kiowski; P Bolli; O Bertel
Journal:  Int J Clin Pharmacol Biopharm       Date:  1979-10

6.  Metabolites of 3-hydrazino-6-[bis-(2-hydroxyethyl)amino]pyridazine dihydrochloride in rat urine.

Authors:  E Beretta; T Cristina; P Ferrari; G Tuan; L F Zerilli; E Martinelli
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1979       Impact factor: 2.441

7.  Quinoxaline studies. 23. Potential antimalarials. Substituted 5,8-dimethoxy-6-[N-(omega-dimethylaminoalkyl)amino]quinoxalines were prepared: the first series with identical 2,3-substituents H, CH3, C6H5, C6H4-4-Cl, and CH2C6H5; and the second with identical styryl groups CH=CHC6H5, CH=CHC6H4-4-Cl, CH=CHC6H3-3,4-Cl2, CH=CHC6H4-4-F, CH=CHC6H4-4-CF3, and CH=CHC6H4-4-NO2. None of the substances possessed antimalarial activity; several were toxic at highest dosage levels.

Authors:  G Pifferi; F Parravicini; C Carpi; L Dorigotti
Journal:  J Med Chem       Date:  1975-07       Impact factor: 7.446

8.  [3-Hydrazinepyridazine derivatives. III. Synthesis and anti-hypertensive activity of new 3-(2-acylhydrazine)-pyridazine-6-alkylamino substitutes].

Authors:  F Parravicini; G Scarpitta; L Dorigotti; G Pifferi
Journal:  Farmaco Sci       Date:  1979-04
  8 in total
  3 in total

1.  Human pharmacokinetics of cadralazine: a new vasodilator.

Authors:  S A Hauffe; J P Dubois; P R Imhof
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1985 Jul-Sep       Impact factor: 2.441

2.  Disposition and pharmacokinetics of cadralazine and individual metabolites in man.

Authors:  H Schütz; J W Faigle; W Küng; W Theobald
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1985 Apr-Jun       Impact factor: 2.441

3.  Pharmacokinetics of cadralazine in hypertensive patients.

Authors:  G Leonetti; J Parini; M Visconti; R Gradnik
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1988 Oct-Dec       Impact factor: 2.441
  3 in total

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