Literature DB >> 8807895

Understanding and controlling the cell cycle with natural products.

D T Hung1, T F Jamison, S L Schreiber.   

Abstract

Small molecule natural products have aided in the discovery and characterization of many proteins critical to the progression and maintenance of the cell cycle. Identification of the direct target of a natural product gives scientists a tool to control a specific aspect of the cell cycle, thus facilitating the study of the cell-cycle machinery.

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Year:  1996        PMID： 8807895     DOI： 10.1016/s1074-5521(96)90129-5

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  32 in total

Review 1.  Chemical genetics: ligand-based discovery of gene function.

Authors:  B R Stockwell
Journal:  Nat Rev Genet       Date:  2000-11       Impact factor: 53.242

2.  Targeting protein inactivation through an oligomerization chain reaction.

Authors:  Francesco Contegno; Mario Cioce; Pier Giuseppe Pelicci; Saverio Minucci
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-12       Impact factor: 11.205

3.  Target-induced formation of neuraminidase inhibitors from in vitro virtual combinatorial libraries.

Authors:  Matthias Hochgürtel; Heiko Kroth; Dorothea Piecha; Michael W Hofmann; Claude Nicolau; Sonja Krause; Otmar Schaaf; Gabriele Sonnenmoser; Alexey V Eliseev
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-12       Impact factor: 11.205

4.  Natural product-inspired cascade synthesis yields modulators of centrosome integrity.

Authors:  Heiko Dückert; Verena Pries; Vivek Khedkar; Sascha Menninger; Hanna Bruss; Alexander W Bird; Zoltan Maliga; Andreas Brockmeyer; Petra Janning; Anthony Hyman; Stefan Grimme; Markus Schürmann; Hans Preut; Katja Hübel; Slava Ziegler; Kamal Kumar; Herbert Waldmann
Journal:  Nat Chem Biol       Date:  2011-12-25       Impact factor: 15.040

5.  High-throughput, library-based selection of a murine leukemia virus variant to infect nondividing cells.

Authors:  Julie H Yu; David V Schaffer
Journal:  J Virol       Date:  2006-09       Impact factor: 5.103

6.  Inhibition of Toxoplasma gondii growth by pyrrolidine dithiocarbamate is cell cycle specific and leads to population synchronization.

Authors:  Magnolia M Conde de Felipe; Margaret M Lehmann; Maria E Jerome; Michael W White
Journal:  Mol Biochem Parasitol       Date:  2007-09-21       Impact factor: 1.759

7.  Mechanism of Action of the Cytotoxic Asmarine Alkaloids.

Authors:  Michael J Lambrecht; Jeffery W Kelly; Ryan A Shenvi
Journal:  ACS Chem Biol       Date:  2018-04-19       Impact factor: 5.100

8.  Actin-aggregating cucurbitacins from Physocarpus capitatus.

Authors:  Katherine N Maloney; Masaki Fujita; Ulrike S Eggert; Frank C Schroeder; Christine M Field; Timothy J Mitchison; Jon Clardy
Journal:  J Nat Prod       Date:  2008-10-29       Impact factor: 4.050

9.  Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors.

Authors:  Karen A Rossi; Jay A Markwalder; Steven P Seitz; Chong-Hwan Chang; Sarah Cox; Michael D Boisclair; Leonardo Brizuela; Stephen L Brenner; Pieter F W Stouten
Journal:  J Comput Aided Mol Des       Date:  2005-02       Impact factor: 3.686

10.  Characterization of synthetic DNA bar codes in Saccharomyces cerevisiae gene-deletion strains.

Authors:  Robert G Eason; Nader Pourmand; Waraporn Tongprasit; Zelek S Herman; Kevin Anthony; Olufisayo Jejelowo; Ronald W Davis; Viktor Stolc
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-16       Impact factor: 11.205
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