OBJECTIVES: This study evaluated the relationship between cancer risk and residential proximity to cranberry cultivation. METHODS: A population-based case-control study was conducted. Cases, diagnosed during 1983 through 1986 among residents of the Upper Cape Cod area of Massachusetts, involved incident cancers of the lung (n = 252), breast (n = 265), colon-rectum (n = 326), bladder (n = 63), kidney (n = 35), pancreas (n = 37), and brain (n = 37), along with leukemia (n = 35). Control subjects were randomly selected from among telephone subscribers (n = 184), Medicare beneficiaries (n = 464), and deceased individuals (n = 723). RESULTS: No meaningful increases in risk were seen for any of the cancer sites except for the brain. When latency was considered, subjects who had ever lived within 2600 ft (780 m) of a cranberry bog had a twofold increased risk of brain cancer overall (95% confidence interval [CI] = 0.8, 4.9) and a 6.7-fold increased risk of astrocytoma (95% CI = 1.6, 27.8). CONCLUSIONS: Residential proximity to cranberry bog cultivation was not associated with seven of the eight cancers investigated; however, an association was observed with brain cancer, particularly astrocytoma. Larger, more detailed studies are necessary to elucidate this relationship.
OBJECTIVES: This study evaluated the relationship between cancer risk and residential proximity to cranberry cultivation. METHODS: A population-based case-control study was conducted. Cases, diagnosed during 1983 through 1986 among residents of the Upper Cape Cod area of Massachusetts, involved incident cancers of the lung (n = 252), breast (n = 265), colon-rectum (n = 326), bladder (n = 63), kidney (n = 35), pancreas (n = 37), and brain (n = 37), along with leukemia (n = 35). Control subjects were randomly selected from among telephone subscribers (n = 184), Medicare beneficiaries (n = 464), and deceased individuals (n = 723). RESULTS: No meaningful increases in risk were seen for any of the cancer sites except for the brain. When latency was considered, subjects who had ever lived within 2600 ft (780 m) of a cranberry bog had a twofold increased risk of brain cancer overall (95% confidence interval [CI] = 0.8, 4.9) and a 6.7-fold increased risk of astrocytoma (95% CI = 1.6, 27.8). CONCLUSIONS: Residential proximity to cranberry bog cultivation was not associated with seven of the eight cancers investigated; however, an association was observed with brain cancer, particularly astrocytoma. Larger, more detailed studies are necessary to elucidate this relationship.
Authors: Jaymie R Meliker; Melissa J Slotnick; Gillian A Avruskin; Andrew Kaufmann; Stacey A Fedewa; Pierre Goovaerts; Geoffrey J Jacquez; Jerome O Nriagu Journal: Int Arch Occup Environ Health Date: 2006-08-09 Impact factor: 3.015
Authors: Emily Russell; Michael R Kramer; Hannah L F Cooper; Winifred Wilkins Thompson; Kimberly R Jacob Arriola Journal: J Urban Health Date: 2011-12 Impact factor: 3.671
Authors: Dorothée Provost; Anne Cantagrel; Pierre Lebailly; Anne Jaffré; Véronique Loyant; Hugues Loiseau; Anne Vital; Patrick Brochard; Isabelle Baldi Journal: Occup Environ Med Date: 2007-05-30 Impact factor: 4.402
Authors: Julia Green Brody; Ann Aschengrau; Wendy McKelvey; Ruthann A Rudel; Christopher H Swartz; Theresa Kennedy Journal: Environ Health Perspect Date: 2004-06 Impact factor: 9.031