| Literature DB >> 8804830 |
K W Uphoff1, S D Bell, A D Ellington.
Abstract
In vitro selection experiments are now routinely used to identify functional nucleic acid residues and structures, and have become a tool for studying molecular recognition, molecular biology, and molecular evolution. Technical innovations that have been made during the past year include the use of modified monomers to increase stability and photocross-linking reagents to improve affinity. These advances should dramatically increase the utility of aptamers in the future.Entities:
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Year: 1996 PMID： 8804830 DOI： 10.1016/s0959-440x(96)80045-5
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809