Literature DB >> 880434

The effects of prostaglandin E1, bradykinin and histamine on canine synovial vascular permeability.

D M Grennan, W Mitchel, W Miller, I J Zeitlin.   

Abstract

1 The relative effects of prostaglandin E1, bradykinin and histamine on canine synovial vascular permeability were investigated by a method based on the measurement of the amounts of radiolabelled dextran (molecular weight 20,000) leaking from the circulation into the synovial cavity. 2 Bradykinin, prostaglandin E1 and histamine in that order of potency all increased synovial vascular permeability. Threshold concentrations were 0.3 micrometer, 3 micrometer and 30 micrometer respectively. 3 The effects of infusion of prostaglandin E1 combined with either bradykinin or histamine were greater than mere summation.

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Year:  1977        PMID： 880434      PMCID： PMC1667423          DOI： 10.1111/j.1476-5381.1977.tb07747.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  8 in total

1.  [Bradykinin].

Authors:  E STURMER
Journal:  Am Heart J       Date:  1961-08       Impact factor: 4.749

2.  Prostaglandins, aspirin-like drugs and the oedema of inflammation.

Authors:  S Moncada; S H Ferreira; J R Vane
Journal:  Nature       Date:  1973-11-23       Impact factor: 49.962

3.  Prostaglandin E-1: a potential mediator of the inflammatory response.

Authors:  G Kaley; R Weiner
Journal:  Ann N Y Acad Sci       Date:  1971-04-30       Impact factor: 5.691

4.  Prostaglandins as potentiators of increased vascular permeability in inflammation.

Authors:  T J Williams; J Morley
Journal:  Nature       Date:  1973-11-23       Impact factor: 49.962

5.  Proceedings: Potentiation by prostaglandins of the nociceptive activity of bradykinin in the dog knee joint.

Authors:  S H Ferreira; S Moncada; J R Vane
Journal:  Br J Pharmacol       Date:  1974-03       Impact factor: 8.739

6.  The presence of a kinin in inflammatory synovial effusion from arthritides of varying etiologies.

Authors:  K L Melmon; M E Webster; S E Goldfinger; J E Seegmiller
Journal:  Arthritis Rheum       Date:  1967-02

7.  Studies on the relative effects of prostaglandins, bradykinin, 5-hydroxytryptamine and histamine on the synovial microcirculation in dogs.

Authors:  W C Dick; D M Grennan; I J Zeitlin
Journal:  Br J Pharmacol       Date:  1976-03       Impact factor: 8.739

8.  On the ability of prostaglandin E1, and arachidonic acid to modulate experimentally induced oedema in the rat paw.

Authors:  A J Lewis; D J Nelson; M F Sugrue
Journal:  Br J Pharmacol       Date:  1975-09       Impact factor: 8.739
  8 in total
  4 in total

1.  Collagen-derived peptides release mast cell histamine.

Authors:  J Wize; E Wojtecka-Lukasik; S Maśliński
Journal:  Agents Actions       Date:  1986-04

2.  Time courses and refractoriness of enhanced vascular permeability induced by histamine, serotonin and bradykinin in synovialis of the rat.

Authors:  L P Bignold; A W Lykke
Journal:  Experientia       Date:  1979-12-15

3.  Plasma extravasation in the cat knee-joint induced by antidromic articular nerve stimulation.

Authors:  W R Ferrell; N J Russell
Journal:  Pflugers Arch       Date:  1985-05       Impact factor: 3.657

4.  Mechanism of enhanced fibroblast arachidonic acid metabolism by mononuclear cell factor.

Authors:  P J Whiteley; P Needleman
Journal:  J Clin Invest       Date:  1984-12       Impact factor: 14.808
  4 in total

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