| Literature DB >> 2425589 |
J Wize, E Wojtecka-Lukasik, S Maśliński.
Abstract
The effect of collagen degradation products by bacterial (BCDP) and synovial fluid collagenase (SCDP) on histamine release from peritoneal mast cells of rat was estimated. Some BCDP as well as SCDP released 60-80% of mast cell histamine. In BCDP fraction the most active were BCDP II (m.wt. 13 kD) and BCDP III (m.wt. 6 kD). The last contained the highest percentage of hydroxyproline. As compared with bradykinin, BCDP III was about 50 fold more active as histamine releaser.Entities:
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Year: 1986 PMID: 2425589 DOI: 10.1007/bf01988037
Source DB: PubMed Journal: Agents Actions ISSN: 0065-4299