Literature DB >> 8800838

Vaccines for gonorrhea: where are we on the curve?

M S Blake1, L M Wetzler.   

Abstract

Human antibodies that bind the gonococcal outer membrane modulate gonorrheal transmission and disease. The effects of antibody binding can favor either the host or the bacteria, and depend on the antigen involved. An effective gonococcal vaccine is feasible, but only by the careful selection and formulation of gonococcal antigens that elicit only host-protective antibodies.

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Year:  1995        PMID： 8800838     DOI： 10.1016/s0966-842x(00)89012-5

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  12 in total

1.  Neisseria meningitidis lipopolysaccharide modulates the specific humoral immune response to neisserial porins but has no effect on porin-induced upregulation of costimulatory ligand B7-2.

Authors:  N Bhasin; Y Ho; L M Wetzler
Journal:  Infect Immun       Date:  2001-08       Impact factor: 3.441

2.  Vaccination with major outer membrane protein proteosomes elicits protection in mice against a Chlamydia respiratory challenge.

Authors:  Delia F Tifrea; Sukumar Pal; Deana N Toussi; Paola Massari; Luis M de la Maza
Journal:  Microbes Infect       Date:  2013-08-30       Impact factor: 2.700

3.  Vaccination in juvenile correctional facilities: state practices, hepatitis B, and the impact on anticipated sexually transmitted infection vaccines.

Authors:  Sara K Tedeschi; Loida E Bonney; Rosario Manalo; Kenneth H Mayer; Susan Shepardson; Josiah D Rich; Michelle A Lally
Journal:  Public Health Rep       Date:  2007 Jan-Feb       Impact factor: 2.792

4.  An in vitro-differentiated human cell line as a model system to study the interaction of Neisseria gonorrhoeae with phagocytic cells.

Authors:  C R Hauck; D Lorenzen; J Saas; T F Meyer
Journal:  Infect Immun       Date:  1997-05       Impact factor: 3.441

5.  Properdin is critical for antibody-dependent bactericidal activity against Neisseria gonorrhoeae that recruit C4b-binding protein.

Authors:  Sunita Gulati; Sarika Agarwal; Shreekant Vasudhev; Peter A Rice; Sanjay Ram
Journal:  J Immunol       Date:  2012-02-24       Impact factor: 5.422

6.  Neisseria gonorrhoeae NspA induces specific bactericidal and opsonic antibodies in mice.

Authors:  Guocai Li; Hongmei Jiao; Guihua Jiang; Jing Wang; Litian Zhu; Rushan Xie; Hua Yan; Hongju Chen; Mingchun Ji
Journal:  Clin Vaccine Immunol       Date:  2011-09-14

Review 7.  Defenses against oxidative stress in Neisseria gonorrhoeae: a system tailored for a challenging environment.

Authors:  Kate L Seib; Hsing-Ju Wu; Stephen P Kidd; Michael A Apicella; Michael P Jennings; Alastair G McEwan
Journal:  Microbiol Mol Biol Rev       Date:  2006-06       Impact factor: 11.056

8.  Comparison of immune responses to gonococcal PorB delivered as outer membrane vesicles, recombinant protein, or Venezuelan equine encephalitis virus replicon particles.

Authors:  Weiyan Zhu; Christopher E Thomas; Ching-Ju Chen; Cornelius N Van Dam; Robert E Johnston; Nancy L Davis; P Frederick Sparling
Journal:  Infect Immun       Date:  2005-11       Impact factor: 3.441

9.  Increased immunoaccessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with Chlamydia muridarum.

Authors:  Delia F Tifrea; Sukumar Pal; Jean-Luc Popot; Melanie J Cocco; Luis M de la Maza
Journal:  J Immunol       Date:  2014-04-28       Impact factor: 5.422

10.  Phase-Variable Heptose I Glycan Extensions Modulate Efficacy of 2C7 Vaccine Antibody Directed against Neisseria gonorrhoeae Lipooligosaccharide.

Authors:  Srinjoy Chakraborti; Lisa A Lewis; Andrew D Cox; Frank St Michael; Jianjun Li; Peter A Rice; Sanjay Ram
Journal:  J Immunol       Date:  2016-05-02       Impact factor: 5.422
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