Literature DB >> 879747

Effects of gestational age, birth weight, and hypoxemia on pharmacokinetics of amikacin in serum of infants.

M G Myers, R J Roberts, N J Mirhij.   

Abstract

The serum pharmacokinetics of amikacin were studied in 36 infants treated for suspected bacterial infection. A prolonged serum half-life was associated with the related variables of birth at an early gestational age, low birth weight, and hypoxemia. A postnatal age effect was not apparent when hypoxemic infants were excluded.

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Year:  1977        PMID： 879747      PMCID： PMC352123          DOI： 10.1128/AAC.11.6.1027

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  27 in total

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Authors:  K THURAU
Journal:  Am J Med       Date:  1964-05       Impact factor: 4.965

2.  Pharmacology of gentamicin in man.

Authors:  L J Riff; G G Jackson
Journal:  J Infect Dis       Date:  1971-12       Impact factor: 5.226

3.  Clinical assessment of gestational age in the newborn infant.

Authors:  L M Dubowitz; V Dubowitz; C Goldberg
Journal:  J Pediatr       Date:  1970-07       Impact factor: 4.406

4.  Comparative pharmacokinetics of amikacin and kanamycin.

Authors:  J T Clarke; R D Libke; C Regamey; W M Kirby
Journal:  Clin Pharmacol Ther       Date:  1974-06       Impact factor: 6.875

5.  Activity of newer aminoglycosides and carbenicillin, alone and in combination, against gentamicin-resistant Pseudomonas aeruginosa.

Authors:  M I Marks; S Hammerberg; G Greenstone; B Silver
Journal:  Antimicrob Agents Chemother       Date:  1976-09       Impact factor: 5.191

6.  Amikacin in newborn infants: comparative pharmacology with kanamycin and clinical efficacy in 45 neonates with bacterial diseases.

Authors:  J B Howard; G H McCraken; H Trujillo; E Mohs
Journal:  Antimicrob Agents Chemother       Date:  1976-08       Impact factor: 5.191

7.  Comparative activity of tobramycin, amikacin, and gentamicin alone and with carbenicillin against Pseudomonas aeruginosa.

Authors:  R M Kluge; H C Standiford; B Tatem; V M Young; W H Greene; S C Schimpff; F M Calia; R B Hornick
Journal:  Antimicrob Agents Chemother       Date:  1974-10       Impact factor: 5.191

8.  Kinetics and dose calculations of amikacin in the newborn.

Authors:  H Sardemann; H Colding; J Hendel; J P Kampmann; E F Hvidberg; R Vejlsgaard
Journal:  Clin Pharmacol Ther       Date:  1976-07       Impact factor: 6.875

9.  Activity of BB-K8 (amikacin) against clinical isolates resistant to one or more aminoglycoside antibiotics.

Authors:  K E Price; T A Pursiano; M D DeFuria
Journal:  Antimicrob Agents Chemother       Date:  1974-02       Impact factor: 5.191

10.  Comparison of five aminocyclitol antibiotics in vitro against Enterobacteriaceae and Pseudomonas.

Authors:  W Karney; K K Holmes; M Turck
Journal:  Antimicrob Agents Chemother       Date:  1973-03       Impact factor: 5.191
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  12 in total

Review 1.  Clinical pharmacokinetics of aminoglycoside antibiotics.

Authors:  J C Pechere; R Dugal
Journal:  Clin Pharmacokinet       Date:  1979 May-Jun       Impact factor: 6.447

Review 2.  Pulmonary disease and drug kinetics.

Authors:  P du Souich; A J McLean; D Lalka; S Erill; M Gibaldi
Journal:  Clin Pharmacokinet       Date:  1978 Jul-Aug       Impact factor: 6.447

3.  Incidence of potentially toxic concentrations of gentamicin in the neonate.

Authors:  A Mulhall; J de Louvois; R Hurley
Journal:  Arch Dis Child       Date:  1983-11       Impact factor: 3.791

4.  Anticonvulsants in the newborn period.

Authors:  N Buchanan
Journal:  Indian J Pediatr       Date:  1985 Sep-Oct       Impact factor: 1.967

5.  Pharmacokinetics and bacteriological efficacy of mezlocillin in experimental Escherichia coli and Listeria monocytogenes meningitis.

Authors:  C Odio; M L Thomas; G H McCracken
Journal:  Antimicrob Agents Chemother       Date:  1984-04       Impact factor: 5.191

6.  Effect of pentobarbital anesthesia on amikacin concentrations in plasma and perilymph and evaluation of multiple sampling in perilymph of guinea pigs.

Authors:  S Desjardins-Giasson; A R Beaubien; M J Cauchy
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

Review 7.  The effect of respiratory disorders on clinical pharmacokinetic variables.

Authors:  A M Taburet; C Tollier; C Richard
Journal:  Clin Pharmacokinet       Date:  1990-12       Impact factor: 6.447

8.  Modification in the pharmacokinetics of amikacin during development.

Authors:  J M Lanao; A Dominguez-Gil; A A Dominguez-Gil; S Málaga; M Crespo; F Nuño
Journal:  Eur J Clin Pharmacol       Date:  1982       Impact factor: 2.953

9.  Pharmacokinetic properties of netilmicin in newborn infants.

Authors:  J D Siegel; G H McCracken; M L Thomas; N Threlkeld
Journal:  Antimicrob Agents Chemother       Date:  1979-02       Impact factor: 5.191

10.  Effects of hypoxemia upon aminoglycoside serum pharmacokinetics in animals.

Authors:  N J Mirhij; R J Roberts; M G Myers
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191
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