Literature DB >> 8796392

The effect of casemix adjustment on mortality as predicted by APACHE II.

D R Goldhill1, P S Withington.   

Abstract

OBJECTIVE: To describe the effect of casemix on mortality as predicted by APACHE II scoring.
DESIGN: Retrospective analysis of an ICU database. PATIENTS AND PARTICIPANTS: All patients admitted to 19 ICU between 1 January 1992 and 31 May 1994 on whom data had been entered into a database. Excluded from the analysis were those readmitted to ICU, those aged under 16 years, those admitted after cardiac surgery or with burns, those for whom physiological data was incomplete and those for whom hospital outcome was unknown. Data on the remaining 6258 patients are reported. MEASUREMENTS AND
RESULTS: APACHE II scores were calculated from the worst values within 24 h of ICU admission. Hospital mortality was predicted with the published equation and coefficients. Mortality ratios (observed hospital deaths divided by predicted hospital deaths) were calculated for various groups. Mortality ratios varied widely by subgroup, and observed hospital deaths were greater than predicted, particularly for the following patient groups: those with predicted mortality of less than 70%, those with APACHE II scores in the range of 5-19, those older than 55 years, those with a Glasgow Coma Score of 15 or in the range 9-14, those not having emergency surgery, those with either 0 or 4 chronic health points and those in non-operative respiratory or neurological categories. The mortality ratio was markedly less than 1.0 only among non-operative cardiovascular patients.
CONCLUSIONS: APACHE II did not accurately adjust for casemix in our data. Unless account is taken of differences in casemix, using mortality ratios to compare ICU is likely to be inaccurate and misleading.

Entities:  

Mesh:

Year:  1996        PMID: 8796392     DOI: 10.1007/bf01712157

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  3 in total

1.  APACHE II: a severity of disease classification system.

Authors:  W A Knaus; E A Draper; D P Wagner; J E Zimmerman
Journal:  Crit Care Med       Date:  1985-10       Impact factor: 7.598

2.  An evaluation of outcome from intensive care in major medical centers.

Authors:  W A Knaus; E A Draper; D P Wagner; J E Zimmerman
Journal:  Ann Intern Med       Date:  1986-03       Impact factor: 25.391

3.  Intensive Care Society's APACHE II study in Britain and Ireland--II: Outcome comparisons of intensive care units after adjustment for case mix by the American APACHE II method.

Authors:  K M Rowan; J H Kerr; E Major; K McPherson; A Short; M P Vessey
Journal:  BMJ       Date:  1993-10-16
  3 in total
  10 in total

1.  Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure.

Authors:  Andres Carrillo; Gumersindo Gonzalez-Diaz; Miquel Ferrer; Maria Elena Martinez-Quintana; Antonia Lopez-Martinez; Noemi Llamas; Maravillas Alcazar; Antoni Torres
Journal:  Intensive Care Med       Date:  2012-02-09       Impact factor: 17.440

2.  Mortality prediction in status epilepticus with the APACHE II score.

Authors:  Jocelyn Y Cheng
Journal:  J Intensive Care Soc       Date:  2017-06-26

3.  Use of the sequential organ failure assessment score as a severity score.

Authors:  André Carlos Kajdacsy-Balla Amaral; Fábio Moreira Andrade; Rui Moreno; Antonio Artigas; Francis Cantraine; Jean-Louis Vincent
Journal:  Intensive Care Med       Date:  2005-01-25       Impact factor: 17.440

4.  Risk of death and the efficacy of eritoran tetrasodium (E5564): design considerations for clinical trials of anti-inflammatory agents in sepsis.

Authors:  Amisha V Barochia; Xizhong Cui; Charles Natanson; Peter Q Eichacker
Journal:  Crit Care Med       Date:  2010-01       Impact factor: 7.598

5.  Effect of the critical care outreach team on patient survival to discharge from hospital and readmission to critical care: non-randomised population based study.

Authors:  Carol Ball; Margaret Kirkby; Susan Williams
Journal:  BMJ       Date:  2003-11-01

6.  External validation of the SAPS II, APACHE II and APACHE III prognostic models in South England: a multicentre study.

Authors:  Dieter H Beck; Gary B Smith; John V Pappachan; Brian Millar
Journal:  Intensive Care Med       Date:  2003-01-18       Impact factor: 17.440

7.  Predictive value of thyroid hormones on the first day in adult respiratory distress syndrome patients admitted to ICU: comparison with SOFA and APACHE II scores.

Authors:  Mevlü Türe; Dilek Memiş; Imran Kurt; Zafer Pamukçu
Journal:  Ann Saudi Med       Date:  2005 Nov-Dec       Impact factor: 1.526

Review 8.  The use of non-invasive ventilation during acute respiratory failure due to pneumonia.

Authors:  Miquel Ferrer; Roberto Cosentini; Stefano Nava
Journal:  Eur J Intern Med       Date:  2012-03-28       Impact factor: 4.487

Review 9.  Clinical review: mass casualty triage--pandemic influenza and critical care.

Authors:  Kirsty Challen; Andrew Bentley; John Bright; Darren Walter
Journal:  Crit Care       Date:  2007       Impact factor: 9.097

10.  Mortality of adult intensive care units in Turkey using the APACHE II and SOFA systems (outcome assessment in Turkish intensive care units).

Authors:  Cetin Kaymak; Irfan Sencan; Seval Izdes; Aydin Sari; Hatice Yagmurdur; Derya Karadas; Derya Oztuna
Journal:  Arch Med Sci       Date:  2016-05-05       Impact factor: 3.318

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.