PURPOSE: To report our preliminary results in the application of a turbo fluid-attenuated inversion-recovery (FLAIR) MR technique to the diagnosis of intracranial tumors and to assess the clinical usefulness of this technique. METHODS: Thirty-four patients with various intracranial tumors were studies with MR imaging, including a turbo FLAIR sequence. FLAIR images were compared with images obtained with conventional spin-echo sequences. RESULTS: Except for 2 lesions in 1 patients, tumor signal intensities on FLAIR images were consistent with those shown on T2-weighted spin-echo images. FLAIR images showed peritumoral edema more clearly than T2-Weighted and proton density-weighted images when the tumor itself was not hyperintense. In 8 of 23 patients in whom edema was associated with tumor, FLAIR images provided better definition between edema and tumor than did T2-weighted and proton density-weighted images. In 5 patients, FLAIR images depicted different signal intensity between cerebrospinal fluid and a cystic or necrotic component. In 20 of 22 patients, postcontrast FLAIR images showed contrast enhancement comparable to that seen on postcontrast T1-weighted images. CONCLUSION: Turbo FLAIR images can supplement conventional spin-echo images in the diagnosis of intracranial tumors.
PURPOSE: To report our preliminary results in the application of a turbo fluid-attenuated inversion-recovery (FLAIR) MR technique to the diagnosis of intracranial tumors and to assess the clinical usefulness of this technique. METHODS: Thirty-four patients with various intracranial tumors were studies with MR imaging, including a turbo FLAIR sequence. FLAIR images were compared with images obtained with conventional spin-echo sequences. RESULTS: Except for 2 lesions in 1 patients, tumor signal intensities on FLAIR images were consistent with those shown on T2-weighted spin-echo images. FLAIR images showed peritumoral edema more clearly than T2-Weighted and proton density-weighted images when the tumor itself was not hyperintense. In 8 of 23 patients in whom edema was associated with tumor, FLAIR images provided better definition between edema and tumor than did T2-weighted and proton density-weighted images. In 5 patients, FLAIR images depicted different signal intensity between cerebrospinal fluid and a cystic or necrotic component. In 20 of 22 patients, postcontrast FLAIR images showed contrast enhancement comparable to that seen on postcontrast T1-weighted images. CONCLUSION: Turbo FLAIR images can supplement conventional spin-echo images in the diagnosis of intracranial tumors.
Authors: Benjamin M Ellingson; Timothy F Cloughesy; Taryar Zaw; Albert Lai; Phioanh L Nghiemphu; Robert Harris; Shadi Lalezari; Naveed Wagle; Kourosh M Naeini; Jose Carrillo; Linda M Liau; Whitney B Pope Journal: Neuro Oncol Date: 2012-01-22 Impact factor: 12.300
Authors: Benjamin M Ellingson; Timothy F Cloughesy; Albert Lai; Phioanh L Nghiemphu; Shadi Lalezari; Taryar Zaw; Kourosh Motevalibashinaeini; Paul S Mischel; Whitney B Pope Journal: J Neurooncol Date: 2011-06-25 Impact factor: 4.130