Literature DB >> 8791491

Cdk inhibitors in development and cancer.

J W Harper1, S J Elledge.   

Abstract

Activation of cyclin-dependent kinases is the primary control point of cell proliferation. Recent advances in the understanding of cell-cycle regulation have uncovered two families of proteins that bind and inhibit these kinases. These proteins are likely mediators of development and differentiation, and may provide molecular connections between the pathways of development and tumorigenesis.

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Year:  1996        PMID： 8791491     DOI： 10.1016/s0959-437x(96)90011-8

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  95 in total

1.  SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.

Authors:  A R Willems; T Goh; L Taylor; I Chernushevich; A Shevchenko; M Tyers
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-09-29       Impact factor: 6.237

2.  BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site.

Authors:  H Ruffner; W Jiang; A G Craig; T Hunter; I M Verma
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

3.  The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells.

Authors:  J Huang; J W Raff
Journal:  EMBO J       Date:  1999-04-15       Impact factor: 11.598

4.  Modulation of the expression of the Cip/Kip family of cyclin-dependent kinase inhibitors in foetal developing lungs of hamsters.

Authors:  T Ikoma; T Ito; K Okudela; H Hayashi; T Yazawa; H Kitamura
Journal:  Cell Prolif       Date:  2001-08       Impact factor: 6.831

5.  Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins.

Authors:  J Hermanns; A Schulze; P Jansen-Db1urr; J A Kleinschmidt; R Schmidt; H zur Hausen
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

Review 6.  Plant D-type cyclins and the control of G1 progression.

Authors:  E Ann Oakenfull; Catherine Riou-Khamlichi; James A H Murray
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2002-06-29       Impact factor: 6.237

Review 7.  The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer.

Authors:  Katrien Vermeulen; Dirk R Van Bockstaele; Zwi N Berneman
Journal:  Cell Prolif       Date:  2003-06       Impact factor: 6.831

8.  Why Do Plant Cells Divide?

Authors:  T. Jacobs
Journal:  Plant Cell       Date:  1997-07       Impact factor: 11.277

9.  p21WAF1/CIP1 selectively controls the transcriptional activity of estrogen receptor alpha.

Authors:  Asmaà Fritah; Cécile Saucier; Jan Mester; Gérard Redeuilh; Michèle Sabbah
Journal:  Mol Cell Biol       Date:  2005-03       Impact factor: 4.272

10.  Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment.

Authors:  Satoru Kase; Kazuhiko Yoshida; Takayuki Harada; Chikako Harada; Kazuhiko Namekata; Yukari Suzuki; Kazuhiro Ohgami; Kenji Shiratori; Keiichi I Nakayama; Shigeaki Ohno
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-08-02       Impact factor: 3.117
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