Literature DB >> 8789639

Function of coenzyme Q in the cell: some biochemical and physiological properties.

H Rauchová1, Z Drahota, G Lenaz.   

Abstract

Coenzyme Q (CoQ), a lipophilic substituted benzoquinone, is well known as a redox component of the mitochondrial and many bacterial respiratory chains. However, additional locations and roles have been recently discovered. CoQ is described as a redox component of extramitochondrial electron transport chains and it is a powerful antioxidant and a membrane stabilizer. Increasing evidence for the beneficial clinical effects of CoQ administration in senescence or in different disorders (e.g. cerebrovascular, muscular, neurogenic) may be explained by the multiple roles of CoQ in cells.

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Year:  1995        PMID: 8789639

Source DB:  PubMed          Journal:  Physiol Res        ISSN: 0862-8408            Impact factor:   1.881


  13 in total

Review 1.  Statin therapy in heart failure: for good, for bad, or indifferent?

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Journal:  Curr Atheroscler Rep       Date:  2014-01       Impact factor: 5.113

2.  Effect of coenzyme Q10 supplementation on diabetes induced memory deficits in rats.

Authors:  Ghazaleh Omidi; Seyed Asaad Karimi; Arezoo Rezvani-Kamran; Amirreza Monsef; Siamak Shahidi; Alireza Komaki
Journal:  Metab Brain Dis       Date:  2019-03-08       Impact factor: 3.584

3.  Co-enzyme Q10 protects primary chicken myocardial cells from heat stress by upregulating autophagy and suppressing the PI3K/AKT/mTOR pathway.

Authors:  Jiao Xu; Bei Huang; Shu Tang; Jiarui Sun; Endong Bao
Journal:  Cell Stress Chaperones       Date:  2019-08-10       Impact factor: 3.667

Review 4.  Coenzyme Q10.

Authors:  Albert E Raizner
Journal:  Methodist Debakey Cardiovasc J       Date:  2019 Jul-Sep

Review 5.  Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems.

Authors:  Adam J Kuszak; Michael Graham Espey; Marni J Falk; Marissa A Holmbeck; Giovanni Manfredi; Gerald S Shadel; Hilary J Vernon; Zarazuela Zolkipli-Cunningham
Journal:  Annu Rev Pathol       Date:  2017-11-03       Impact factor: 23.472

6.  Coenzyme Q-dependent functions of plasma membrane in the aging process.

Authors:  Plácido Navas; José Manuel Villalba; Giorgio Lenaz
Journal:  Age (Dordr)       Date:  2005-12-10

Review 7.  Coenzyme Q10 and Utility in Heart Failure: Just Another Supplement?

Authors:  Sylvia Oleck; Hector O Ventura
Journal:  Curr Heart Fail Rep       Date:  2016-08

8.  Effect of high-dose vitamins, coenzyme Q and high-fat diet in paediatric patients with mitochondrial diseases.

Authors:  J Panetta; L J Smith; A Boneh
Journal:  J Inherit Metab Dis       Date:  2004       Impact factor: 4.982

9.  Protective effect of L-carnitine and coenzyme Q10 on CCl₄-induced liver injury in rats.

Authors:  Sanaa Ahmed Ali; Lilla Faddah; Ateff Abdel-Baky; Asmaa Bayoumi
Journal:  Sci Pharm       Date:  2010-08-23

Review 10.  New treatments for mitochondrial disease-no time to drop our standards.

Authors:  Gerald Pfeffer; Rita Horvath; Thomas Klopstock; Vamsi K Mootha; Anu Suomalainen; Saskia Koene; Michio Hirano; Massimo Zeviani; Laurence A Bindoff; Patrick Yu-Wai-Man; Michael Hanna; Valerio Carelli; Robert McFarland; Kari Majamaa; Douglas M Turnbull; Jan Smeitink; Patrick F Chinnery
Journal:  Nat Rev Neurol       Date:  2013-07-02       Impact factor: 42.937

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