Literature DB >> 8789438

Cloning and characterization of a murine brain specific gene Bpx and its human homologue lying within the Xic candidate region.

C Rougeulle1, P Avner.   

Abstract

The X inactivation centre (Xic) is a cis-acting locus thought to play a key role in the initiation of X-inactivation. We have cloned and characterized a new gene, Bpx, lying distal to the murine Xist. Bpx, which is specifically expressed in the brain, shows strong homology to genes encoding nucleosome assembly proteins and is normally X-inactivated in mice. Isolation and localization of BPX, its human homologue, has shown the gene to be located centromeric to XIST in man. The Xq13 region, whose orientation is apparently globally conserved between man and mouse, must therefore contain an inversion of at least 600 kb spanning the XIST sequence and including the CDX4 and BPX genes.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8789438     DOI： 10.1093/hmg/5.1.41

Source DB:  PubMed          Journal:  Hum Mol Genet        ISSN： 0964-6906            Impact factor:   6.150


  7 in total

1.  A developmental switch in H4 acetylation upstream of Xist plays a role in X chromosome inactivation.

Authors:  L P O'Neill; A M Keohane; J S Lavender; V McCabe; E Heard; P Avner; N Brockdorff; B M Turner
Journal:  EMBO J       Date:  1999-05-17       Impact factor: 11.598

2.  Identification of an S19 pseudogene lying close to the Xist sequence in the mouse.

Authors:  C Rougeulle; P Avner
Journal:  Mamm Genome       Date:  1996-08       Impact factor: 2.957

3.  Developmentally controlled farnesylation modulates AtNAP1;1 function in cell proliferation and cell expansion during Arabidopsis leaf development.

Authors:  Arnaud Galichet; Wilhelm Gruissem
Journal:  Plant Physiol       Date:  2006-10-13       Impact factor: 8.340

4.  Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine.

Authors:  Corinne Chureau; Marine Prissette; Agnès Bourdet; Valérie Barbe; Laurence Cattolico; Louis Jones; André Eggen; Philip Avner; Laurent Duret
Journal:  Genome Res       Date:  2002-06       Impact factor: 9.043

5.  Isolation, X location and activity of the marsupial homologue of SLC16A2, an XIST-flanking gene in eutherian mammals.

Authors:  Edda Koina; Matthew J Wakefield; Cristina Walcher; Christine M Disteche; Siobhan Whitehead; Mark Ross; Jennifer A Marshall Graves
Journal:  Chromosome Res       Date:  2005-10-24       Impact factor: 5.239

6.  Nap1l2 promotes histone acetylation activity during neuronal differentiation.

Authors:  Mikaël Attia; Christophe Rachez; Antoine De Pauw; Philip Avner; Ute Christine Rogner
Journal:  Mol Cell Biol       Date:  2007-06-25       Impact factor: 4.272

7.  A mechanistic role for the chromatin modulator, NAP1L1, in pancreatic neuroendocrine neoplasm proliferation and metastases.

Authors:  Simon Schimmack; Andrew Taylor; Ben Lawrence; Daniele Alaimo; Hubertus Schmitz-Winnenthal; Markus W Büchler; Irvin M Modlin; Mark Kidd
Journal:  Epigenetics Chromatin       Date:  2014-07-21       Impact factor: 4.954
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.