| Literature DB >> 8789197 |
V Kahn1.
Abstract
Kojic acid inhibits effectively the rate of formation of pigmented product(s) and of oxygen uptake when DL-DOPA, norepinephrine and dopamine are oxidized by mushroom tyrosinase. In addition to the direct effect of kojic acid on the enzyme, kojic acid also affects the UV-VIS spectrum of the final product(s) formed, this being due to the ability of the o-quinones of these substrates to oxidize kojic acid to a yellow product(s). Kojic acid can thus prevent the conversion of the o-quinones of DL-DOPA, norepinephrine and dopamine to their corresponding melanin.Entities:
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Year: 1995 PMID： 8789197 DOI： 10.1111/j.1600-0749.1995.tb00669.x
Source DB: PubMed Journal: Pigment Cell Res ISSN： 0893-5785