Literature DB >> 8785609

Mapping of the porcine urate oxidase and transforming growth factor beta 2 genes by fluorescence in situ hybridization.

G Rettenberger1, T Leeb, S Meier-Ewert, J Bruch, C Klett, B Brenig, H Hameister.   

Abstract

We have mapped two genes from human chromosome 1, urate oxidase (UOX) and transforming growth factor beta 2 (TGFB2), by fluorescence in situ hybridization (FISH) in the pig genome. Porcine-specific polymerase chain reaction (PCR) primers for both genes were designed from the porcine cDNA sequence. With the help of these primers yeast artificial chromosome (YAC) clones for UOX and TGFB2 were isolated from a pig YAC library. These DNA probes were used for FISH analysis. TGFB2 was localized to SSC 10p16. With the YAC probe for UOX two porcine chromosome regions 6q26 and 6q32, revealed specific signals. These results, help to refine the comparative mapping data between human and pig.

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Year:  1996        PMID: 8785609     DOI: 10.1007/bf02259708

Source DB:  PubMed          Journal:  Chromosome Res        ISSN: 0967-3849            Impact factor:   5.239


  14 in total

1.  Localization of the human urate oxidase gene (UOX) to 1p22.

Authors:  A V Yeldandi; Y D Patel; M Liao; F T Kao; M S Rao; J K Reddy; M M Le Beau
Journal:  Cytogenet Cell Genet       Date:  1992

2.  High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones.

Authors:  P Lichter; C J Tang; K Call; G Hermanson; G A Evans; D Housman; D C Ward
Journal:  Science       Date:  1990-01-05       Impact factor: 47.728

3.  Construction of a porcine YAC library and mapping of the cardiac muscle ryanodine receptor gene to chromosome 14q22-q23.

Authors:  T Leeb; G Rettenberger; H Hameister; G Brem; B Brenig
Journal:  Mamm Genome       Date:  1995-01       Impact factor: 2.957

4.  Assignment of the Leydig insulin-like hormone to porcine chromosome 2q12-q13 by somatic cell hybrid analysis and fluorescence in situ hybridization.

Authors:  G Rettenberger; E Burkhardt; I M Adham; W Engel; R Fries; C Klett; H Hameister
Journal:  Mamm Genome       Date:  1994-05       Impact factor: 2.957

Review 5.  Anchored reference loci for comparative genome mapping in mammals.

Authors:  S J O'Brien; J E Womack; L A Lyons; K J Moore; N A Jenkins; N G Copeland
Journal:  Nat Genet       Date:  1993-02       Impact factor: 38.330

6.  Comparative mapping reveals extensive linkage conservation--but with gene order rearrangements--between the pig and the human genomes.

Authors:  M Johansson; H Ellegren; L Andersson
Journal:  Genomics       Date:  1995-02-10       Impact factor: 5.736

Review 7.  Mammalian genome mapping: lessons and prospects.

Authors:  S J O'Brien
Journal:  Curr Opin Genet Dev       Date:  1991-06       Impact factor: 5.578

8.  Visualization of the conservation of synteny between humans and pigs by heterologous chromosomal painting.

Authors:  G Rettenberger; C Klett; U Zechner; J Kunz; W Vogel; H Hameister
Journal:  Genomics       Date:  1995-03-20       Impact factor: 5.736

9.  Standard karyotype of the domestic pig. Committee for the Standardized Karyotype of the Domestic Pig.

Authors:  I Gustavsson
Journal:  Hereditas       Date:  1988       Impact factor: 3.271

10.  Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family.

Authors:  D E Barton; B E Foellmer; J Du; J Tamm; R Derynck; U Francke
Journal:  Oncogene Res       Date:  1988
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  1 in total

1.  The cytogenetic map of the domestic pig.

Authors:  M Yerle; Y Lahbib-Mansais; P Pinton; A Robic; A Goureau; D Milan; J Gellin
Journal:  Mamm Genome       Date:  1997-08       Impact factor: 2.957

  1 in total

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