Literature DB >> 8784901

An immunohistochemical analysis of anti-amylase antibody reactivity in acinic cell adenocarcinoma.

E L Childers1, G L Ellis, P L Auclair.   

Abstract

In many salivary acinic cell adenocarcinomas, well-differentiated serous acinar-type cells may be few and inconspicuous. In these cases it may be difficult to distinguish acinic cell adenocarcinoma from other types of salivary gland neoplasms such as cystadenocarcinoma. The usefulness of antisalivary amylase antibody immunohistochemical staining as a diagnostic aid was assessed on paraffin-embedded tissue sections from 27 typical acinic cell adenocarcinomas. Only 4 of 27 tumors showed reactivity in tumor cells. We conclude that anti-amylase antibody is of limited value in the recognition of acinic cell adenocarcinoma when light morphologic features are insufficient for diagnosis.

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Year:  1996        PMID: 8784901     DOI: 10.1016/s1079-2104(96)80075-8

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod        ISSN: 1079-2104


  3 in total

1.  Well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland in children: a case report and literature review.

Authors:  Zhengjin Liu; Chao Pan; Ping Yin; Hongfeng Liao
Journal:  Int J Clin Exp Pathol       Date:  2018-03-01

Review 2.  [Salivary gland tumors--tumor typing and grading].

Authors:  T Löning; K T Jäkel
Journal:  Pathologe       Date:  2004-02       Impact factor: 1.011

3.  Immunohistochemical analysis of salivary gland tumors: application for surgical pathology practice.

Authors:  Toshitaka Nagao; Eiichi Sato; Rie Inoue; Hisashi Oshiro; Reisuke H Takahashi; Takeshi Nagai; Maki Yoshida; Fumie Suzuki; Hiyo Obikane; Mitsumasa Yamashina; Jun Matsubayashi
Journal:  Acta Histochem Cytochem       Date:  2012-09-22       Impact factor: 1.938

  3 in total

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