Literature DB >> 8784346

The hairpin stack fold, a novel protein architecture for a new family of protein growth factors.

R Hrabal, Z Chen, S James, H P Bennett, F Ni.   

Abstract

The granulin/epithelin protein motif has an unusual structure consisting of a parallel stack of beta-hairpins stapled together by six disulphide bonds. The new structure also contains a folding subdomain shared by small toxins, protease inhibitors as well as the EGF-like protein modules.

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Year:  1996        PMID： 8784346     DOI： 10.1038/nsb0996-747

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


  66 in total

1.  A slow maturation of a cysteine protease with a granulin domain in the vacuoles of senescing Arabidopsis leaves.

Authors:  K Yamada; R Matsushima; M Nishimura; I Hara-Nishimura
Journal:  Plant Physiol       Date:  2001-12       Impact factor: 8.340

2.  Classification of protein disulphide-bridge topologies.

Authors:  J M Mas; P Aloy; M A Martí-Renom; B Oliva; R de Llorens; F X Avilés; E Querol
Journal:  J Comput Aided Mol Des       Date:  2001-05       Impact factor: 3.686

3.  Functional characterization and molecular mechanism exploration of three granulin epithelin precursor splice variants in biomineralization of the pearl oyster Pinctada fucata.

Authors:  Mi Zhao; Maoxian He; Xiande Huang; Qi Wang; Yu Shi
Journal:  Mol Genet Genomics       Date:  2015-09-20       Impact factor: 3.291

Review 4.  Progranulin: a growth factor, a novel TNFR ligand and a drug target.

Authors:  Chuan-ju Liu; Xavier Bosch
Journal:  Pharmacol Ther       Date:  2011-10-08       Impact factor: 12.310

5.  Structure dissection of zebrafish progranulins identifies a well-folded granulin/epithelin module protein with pro-cell survival activities.

Authors:  Ping Wang; Babykumari Chitramuthu; Andrew Bateman; Hugh P J Bennett; Ping Xu; Feng Ni
Journal:  Protein Sci       Date:  2018-07-18       Impact factor: 6.725

6.  Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis.

Authors:  Jian Q Feng; Feng-Jin Guo; Bai-Chun Jiang; Yan Zhang; Sally Frenkel; Da-Wei Wang; Wei Tang; Yixia Xie; Chuan-Ju Liu
Journal:  FASEB J       Date:  2010-02-02       Impact factor: 5.191

7.  Pathogenic cysteine mutations affect progranulin function and production of mature granulins.

Authors:  Jun Wang; Philip Van Damme; Carlos Cruchaga; Michael A Gitcho; Jose Manuel Vidal; Manuel Seijo-Martínez; Lei Wang; Jane Y Wu; Wim Robberecht; Alison Goate
Journal:  J Neurochem       Date:  2009-12-17       Impact factor: 5.372

Review 8.  Progranulin: A key player in autoimmune diseases.

Authors:  Jinlong Jian; Guangfei Li; Aubryanna Hettinghouse; Chuanju Liu
Journal:  Cytokine       Date:  2016-08-12       Impact factor: 3.861

9.  Fully reduced granulin-B is intrinsically disordered and displays concentration-dependent dynamics.

Authors:  Gaurav Ghag; Lauren M Wolf; Randi G Reed; Nicholas P Van Der Munnik; Claudius Mundoma; Melissa A Moss; Vijayaraghavan Rangachari
Journal:  Protein Eng Des Sel       Date:  2016-03-07       Impact factor: 1.650

10.  Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.

Authors:  Yasuko Yamamoto; Masao Takemura; Ginette Serrero; Jun Hayashi; Binbin Yue; Aya Tsuboi; Hisako Kubo; Takashi Mitsuhashi; Kenji Mannami; Masao Sato; Hidetoshi Matsunami; Yushi Matuo; Kuniaki Saito
Journal:  Inflammation       Date:  2014-10       Impact factor: 4.092
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