Literature DB >> 8783370

GABAA receptor pharmacology.

G A Johnston1.   

Abstract

gamma-Aminobutyric acid (GABA)A receptors for the inhibitory neurotransmitter GABA are likely to be found on most, if not all, neurons in the brain and spinal cord. They appear to be the most complicated of the superfamily of ligand-gated ion channels in terms of the large number of receptor subtypes and also the variety of ligands that interact with specific sites on the receptors. There appear to be at least 11 distinct sites on GABAA receptors for these ligands.

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Year:  1996        PMID: 8783370     DOI: 10.1016/0163-7258(95)02043-8

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN: 0163-7258            Impact factor:   12.310


  60 in total

Review 1.  General anaesthetic actions on ligand-gated ion channels.

Authors:  M D Krasowski; N L Harrison
Journal:  Cell Mol Life Sci       Date:  1999-08-15       Impact factor: 9.261

2.  Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant.

Authors:  Ryan W Lewis; John Mabry; Jason G Polisar; Kyle P Eagen; Bruce Ganem; George P Hess
Journal:  Biochemistry       Date:  2010-06-15       Impact factor: 3.162

3.  Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.

Authors:  R F Squires; J Ai; M R Witt; P Kahnberg; E Saederup; O Sterner; M Nielsen
Journal:  Neurochem Res       Date:  1999-12       Impact factor: 3.996

4.  Inhibition of the GABAA Receptor by Sulfated Neurosteroids: A Mechanistic Comparison Study between Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate.

Authors:  Divya Sachidanandan; Amal Kanti Bera
Journal:  J Mol Neurosci       Date:  2015-03-01       Impact factor: 3.444

Review 5.  Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships.

Authors:  Renê Oliveira Beleboni; Ruither Oliveira Gomes Carolino; Andrea Baldocchi Pizzo; Lissandra Castellan-Baldan; Joaquim Coutinho-Netto; Wagner Ferreira dos Santos; Norberto Cysne Coimbra
Journal:  Cell Mol Neurobiol       Date:  2004-12       Impact factor: 5.046

6.  A thermosensory pathway that controls body temperature.

Authors:  Kazuhiro Nakamura; Shaun F Morrison
Journal:  Nat Neurosci       Date:  2007-12-16       Impact factor: 24.884

7.  Enantioselective organocatalytic Michael addition of aldehydes to nitroethylene: efficient access to gamma2-amino acids.

Authors:  Yonggui Chi; Li Guo; Nathan A Kopf; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2008-04-04       Impact factor: 15.419

Review 8.  GABA-ρ receptors: distinctive functions and molecular pharmacology.

Authors:  Moawiah M Naffaa; Sandy Hung; Mary Chebib; Graham A R Johnston; Jane R Hanrahan
Journal:  Br J Pharmacol       Date:  2017-04-12       Impact factor: 8.739

9.  Investigations into the mechanism of 2,3-dimercaptopropanol neurotoxicity.

Authors:  C W Nogueira; F A Soares; R C Bolzan; M C Jacques-Silva; D O Souza; J B Rocha
Journal:  Neurochem Res       Date:  2000-12       Impact factor: 3.996

10.  Gonadal hormone-independent sex differences in GABAA receptor activation in rat embryonic hypothalamic neurons.

Authors:  Franco R Mir; Carlos Wilson; Lucas E Cabrera Zapata; Luis G Aguayo; María Julia Cambiasso
Journal:  Br J Pharmacol       Date:  2020-04-03       Impact factor: 8.739

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