| Literature DB >> 8778237 |
J L McCormick1, T C McKee, J H Cardellina, M R Boyd.
Abstract
Bioassay-directed fractionation of the CH2Cl2-MeOH extract of Euodia roxburghiana resulted in the isolation of two known quinoline alkaloids, buchapine (1) and 2, and three new furoquinoline alkaloids, roxiamines A, B, and C (3-5). Compounds 1 and 2 protected CEM-SS cells from the cytopathic effects of HIV-1 in vitro (EC50 0.94 and 1.64 microM, respectively), but 3-5 were inactive against HIV-1.Entities:
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Year: 1996 PMID: 8778237 DOI: 10.1021/np960250m
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050