PURPOSE: To evaluate the feasibility of MRI-based myocardial first-pass contrast perfusion imaging with a multi-shot echo planar imaging (EPI) technique. SUBJECTS AND METHODS: A non-sequential (ECG-triggered) gradient echo two-shot EPI acquisition strategy capable of covering the entire heart in contiguous 10-mm sections every two cardiac cycles with an in-plane resolution of 1.56 X 1.56 mm was implemented on a 1.5-T Signa Advantage Scanner equipped with prototype hardware for non-resonant EPI in the transverse plane. The heart of a single volunteer was studied prior to and following the intravenous bolus application of a paramagnetic contrast agent (Gd-DOTA, 0.2 mmol/kg). RESULTS: Twelve contiguous transaxial 10-mm EPI images were obtained every two RR intervals for a total of 40 s. The myocardial contrast perfusion study was technically adequate. Contrast caused a signal loss of 87% in the right and 67% in the left ventricle and 59% in the myocardium. CONCLUSION: First-pass myocardial perfusion imaging with a gradient echo, two-shot echo planar imaging strategy is feasible.
PURPOSE: To evaluate the feasibility of MRI-based myocardial first-pass contrast perfusion imaging with a multi-shot echo planar imaging (EPI) technique. SUBJECTS AND METHODS: A non-sequential (ECG-triggered) gradient echo two-shot EPI acquisition strategy capable of covering the entire heart in contiguous 10-mm sections every two cardiac cycles with an in-plane resolution of 1.56 X 1.56 mm was implemented on a 1.5-T Signa Advantage Scanner equipped with prototype hardware for non-resonant EPI in the transverse plane. The heart of a single volunteer was studied prior to and following the intravenous bolus application of a paramagnetic contrast agent (Gd-DOTA, 0.2 mmol/kg). RESULTS: Twelve contiguous transaxial 10-mm EPI images were obtained every two RR intervals for a total of 40 s. The myocardial contrast perfusion study was technically adequate. Contrast caused a signal loss of 87% in the right and 67% in the left ventricle and 59% in the myocardium. CONCLUSION: First-pass myocardial perfusion imaging with a gradient echo, two-shot echo planar imaging strategy is feasible.
Authors: C P Davis; G C McKinnon; J F Debatin; D Wetter; A C Eichenberger; S Duewell; G K von Schulthess Journal: Radiology Date: 1994-06 Impact factor: 11.105
Authors: A C Eichenberger; E Schuiki; V D Köchli; F W Amann; G C McKinnon; G K von Schulthess Journal: J Magn Reson Imaging Date: 1994 May-Jun Impact factor: 4.813