Literature DB >> 8772948

Local steroid therapy in cutaneous hemangiomas.

A N Gangopadhyay1, S P Sharma, S C Gopal, D K Gupta, K Panjawani, J K Sinha.   

Abstract

OBJECTIVES: To evaluate the efficacy of intralesional triamcinolone in enhancing regression in various type of hemangiomas.
SETTING: Outpatients department of a teaching hospital Subjects: One hundred and five patients with rapidly growing surface hemangioma. The age ranged from 1 month to 15 months (mean 7 months). INTERVENTION: Intralesional triamcinolone administered at monthly intervals, ranging from single injection to 7 injections (mean 3.6 injections). MAIN OUTCOME MEASURE: Regression of the hemangioma.
RESULTS: The overall response rate was 88.6% (excellent 51.4%, and good 37.2%). Maximum response was observed in children below 1 year of age (> 90%), lesions over the face (92.8%) and strawberry hemangiomas (99.9%).
CONCLUSION: Intralesional administration of triamcinolone devoid of systemic side effects and an effective initial modality for rapidly growing hermangiomas.

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Year:  1996        PMID: 8772948

Source DB:  PubMed          Journal:  Indian Pediatr        ISSN: 0019-6061            Impact factor:   1.411


  5 in total

Review 1.  Corticosteroid treatment of periorbital haemangioma of infancy: a review of the evidence.

Authors:  T M Ranchod; I J Frieden; D R Fredrick
Journal:  Br J Ophthalmol       Date:  2005-09       Impact factor: 4.638

2.  Multiple Verrucous Hemangiomas: A Case Report with New Therapeutic Insight.

Authors:  Jasmeet Singh; Preeti Sharma; Sidharth Tandon; Surabhi Sinha
Journal:  Indian Dermatol Online J       Date:  2017 Jul-Aug

3.  Evaluation of the efficacy and safety of topical timolol maleate combined with oral propranolol treatment for parotid mixed infantile hemangiomas.

Authors:  Shuang Tong; Da-Peng Xu; Zi-Mei Liu; Yang Du; Xu-Kai Wang
Journal:  Oncol Lett       Date:  2016-07-07       Impact factor: 2.967

4.  The Safety of Intralesional Steroid Injections in Young Children and Their Effectiveness in Anastomotic Esophageal Strictures-A Meta-Analysis and Systematic Review.

Authors:  Annefleur R L van Hal; Rebecca Pulvirenti; Floris P J den Hartog; John Vlot
Journal:  Front Pediatr       Date:  2022-01-28       Impact factor: 3.418

5.  Clinical Profile of Paediatric Hemangiomas, Response to Oral Propranolol, and Comparison of Intralesional Bleomycin and Triamcinolone in Propranolol Non Responders at a Tertiary Care Center in North India.

Authors:  Gulab Dhar Yadav; Shraddha Verma; Ashish Varshney; Adiveeth Deb
Journal:  J Indian Assoc Pediatr Surg       Date:  2022-07-26
  5 in total

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