Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Immunocytochemical demonstration that human duodenal Brunner's glands may participate in intestinal defence.

Literature DB >> 8771411

Immunocytochemical demonstration that human duodenal Brunner's glands may participate in intestinal defence.

H B Coutinho¹, T I Robalinho, V B Coutinho, A M Amorin, J R Almeida, J T Filho, E Walker, G King, H F Sewell, D Wakelin.

Abstract

The immunocytochemical demonstration of IgA and IgM in some secretory units of human Brunner's glands, associated with the presence of secretory component in all secretory cells, indicates the possibility that these glands assist the function of the intestinal crypts in transporting immunoglobulins into the gut lumen. In addition, the presence of muramidase (lysozyme) in the cells of the secretory units suggests that Brunner's glands continuously secrete bactericidal enzyme, thus reinforcing the function of the Paneth cells as contributors to nonspecific defence (innate immunity) in the intestinal tract.

Entities: Species

Mesh：

Substances：

Year: 1996 PMID： 8771411 PMCID： PMC1167842

Source DB: PubMed Journal: J Anat ISSN： 0021-8782 Impact factor: 2.610

2 in total

1. Relation between HLA-DR-like antigens and secretory component (SC) in jejunal epithelium of patients with coeliac disease or dermatitis herpetiformis.

Authors: H Scott; P Brandtzaeg; B G Solheim; E Thorsby
Journal: Clin Exp Immunol Date: 1981-05 Impact factor: 4.330

2. Determination of the histological distribution of insulin like growth factor 1 receptors in the rat gut.

Authors: J Ryan; D C Costigan
Journal: Gut Date: 1993-12 Impact factor: 23.059

2 in total

9 in total

1. Munc18/SNARE proteins' regulation of exocytosis in guinea pig duodenal Brunner's gland acini.

Authors: Laura-I Cosen-Binker; Gerry P Morris; Stephen Vanner; Herbert Y Gaisano
Journal: World J Gastroenterol Date: 2008-04-21 Impact factor: 5.742

2. Immunocytochemistry of mucosal changes in patients infected with the intestinal nematode Strongyloides stercoralis.

Authors: H B Coutinho; T I Robalinho; V B Coutinho; J R Almeida; J T Filho; G King; D Jenkins; Y Mahida; H F Sewell; D Wakelin
Journal: J Clin Pathol Date: 1996-09 Impact factor: 3.411

3. Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium.

Authors: Koji Hase; Lars Eckmann; John D Leopard; Nissi Varki; Martin F Kagnoff
Journal: Infect Immun Date: 2002-02 Impact factor: 3.441

Immunocytochemical demonstration that human duodenal Brunner's glands may participate in intestinal defence.

1. Relation between HLA-DR-like antigens and secretory component (SC) in jejunal epithelium of patients with coeliac disease or dermatitis herpetiformis.

2. Determination of the histological distribution of insulin like growth factor 1 receptors in the rat gut.

1. Munc18/SNARE proteins' regulation of exocytosis in guinea pig duodenal Brunner's gland acini.

2. Immunocytochemistry of mucosal changes in patients infected with the intestinal nematode Strongyloides stercoralis.

3. Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium.

4. Stereologic characteristics of pig small intestine during normal development.

5. Regulated traffic of anion transporters in mammalian Brunner's glands: a role for water and fluid transport.

6. Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract.

7. Absence of lysozyme (muramidase) in the intestinal Paneth cells of newborn infants with necrotising enterocolitis.

8. Expression of glutathione S-transferase alpha, P1-1 and T1-1 in the human gastrointestinal tract.

Review 9. Metaplastic Paneth Cells in Extra-Intestinal Mucosal Niche Indicate a Link to Microbiome and Inflammation.