Literature DB >> 8767847

Synthesis and anticancer properties of pyrimido[4,5-b]quinolines.

A Długosz1, D Duś.   

Abstract

The synthesis and antitumor properties of pyrimido[4,5-b]quinolines have been described starting from 4-arylamino-5-carboxy-2-hydroxy-6-methylpyrimidines by reaction with PPA or POCl3. The reduced pyrimidoquinolines and derivatives with alkylating function have also been obtained.

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Year:  1996        PMID: 8767847

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  3 in total

1.  The novel calcineurin inhibitor CN585 has potent immunosuppressive properties in stimulated human T cells.

Authors:  Frank Erdmann; Matthias Weiwad; Susann Kilka; Magdalena Karanik; Michael Pätzel; Ria Baumgrass; Jürgen Liebscher; Gunter Fischer
Journal:  J Biol Chem       Date:  2009-11-18       Impact factor: 5.157

2.  Facile synthesis of 5, 6, 7, 8-tetrahydropyrimido [4, 5-b]-quinoline derivatives.

Authors:  Yehya Mahmud Elkholy; Mohamed Abdelhamed Morsy
Journal:  Molecules       Date:  2006-11-17       Impact factor: 4.411

3.  Crystal structure of hexa-aqua-nickel(II) bis{2-[(5,6-di-hy-droxy-3-sul-fon-ato-quino-lin-1-ium-7-yl)oxy]acetate} dihydrate.

Authors:  Hai Le Thi Hong; Vinh Nguyen Thi Ngoc; Da Tran Thi; Ngan Nguyen Bich; Luc Van Meervelt
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-08-26
  3 in total

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