Literature DB >> 8762743

Screening for colorectal cancer: a general-practice-based study.

J Marjoram1, R Strachan, A Allan, E Allan.   

Abstract

BACKGROUND: A 2-year study was undertaken to determine the best way of setting up faecal occult blood screening for colorectal cancer in a single general practice in north Birmingham, a district with no pre-existing hospital-based screening programme for colorectal cancer. This programme was set up in close collaboration with the Departments of Surgery and Biochemistry at the local Good Hope Hospital Trust. This facilitated joint meetings between the staff of these hospital departments and the practice manager, who was responsible for organization of the study at the Hawthorns Surgery and also supervised the day-to-day running of the programme. Essentially, the study was organized and run by the practice manager and nurse. AIM: The study was undertaken to prepare the way for other general practices in north Birmingham to screen selected populations for colorectal cancer.
METHOD: A Haemoccult test kit was posted to patients together with an explanatory letter. The design of the screening programme was similar to the design of the 'screened arm' of the Medical Research Council (MRC) colorectal screening trial in Nottingham. On completion of the programme, questionnaires were posted to 100 responders and 100 non-responders to assess the level of patient acceptability for the screening study. A total of 3509 patients (1599 men and 1910 women) were invited to take part in the screening.
RESULTS: The response rate was 55.4%. Thirty-nine patients were referred from the screening study for further investigation. Colonoscopy identified nine adenomas in nine patients, and a further 12 patients were found to have colorectal carcinoma.
CONCLUSIONS: The findings from the study suggest that this method could be used as a model for other general practices introducing colorectal screening using Haemoccult.

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Year:  1996        PMID: 8762743      PMCID: PMC1239635     

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN: 0960-1643            Impact factor:   5.386


  8 in total

1.  General practitioners' awareness of colorectal cancer: a 10 year review.

Authors:  A R Dixon; J Thornton-Holmes; N M Cheetham
Journal:  BMJ       Date:  1990-07-21

Review 2.  Psychological costs of screening.

Authors:  T M Marteau
Journal:  BMJ       Date:  1989-08-26

3.  Screening and genetic counselling for relatives of patients with colorectal cancer in a family cancer clinic.

Authors:  R S Houlston; V Murday; C Harocopos; C B Williams; J Slack
Journal:  BMJ       Date:  1990 Aug 18-25

4.  Randomised, controlled trial of faecal occult blood screening for colorectal cancer. Results for first 107,349 subjects.

Authors:  J D Hardcastle; W M Thomas; J Chamberlain; G Pye; J Sheffield; P D James; T W Balfour; S S Amar; N C Armitage; S M Moss
Journal:  Lancet       Date:  1989-05-27       Impact factor: 79.321

5.  Acceptability of opportunistic screening for occult gastrointestinal blood loss.

Authors:  F D Hobbs; R C Cherry; J W Fielding; L Pike; R Holder
Journal:  BMJ       Date:  1992-02-22

6.  The results of 1115 patients with colorectal cancer treated over an 8-year period in a single hospital.

Authors:  M J Stower; J D Hardcastle
Journal:  Eur J Surg Oncol       Date:  1985-06       Impact factor: 4.424

7.  Hypertension: psychological aspects and diagnostic impact in a clinical trial.

Authors:  A Mann
Journal:  Psychol Med Monogr Suppl       Date:  1984

Review 8.  Screening an asymptomatic population for colorectal cancer.

Authors:  J D Hardcastle; W M Thomas
Journal:  Baillieres Clin Gastroenterol       Date:  1989-07
  8 in total
  2 in total

1.  Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: cluster randomised controlled trial.

Authors:  David A Fitzmaurice; F D Richard Hobbs; Sue Jowett; Jonathon Mant; Ellen T Murray; Roger Holder; J P Raftery; S Bryan; Michael Davies; Gregory Y H Lip; T F Allan
Journal:  BMJ       Date:  2007-08-02

2.  A randomised controlled trial and cost effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in the over 65s: (SAFE) [ISRCTN19633732].

Authors:  Dawn Swancutt; Richard Hobbs; David Fitzmaurice; Jonathan Mant; Ellen Murray; Sue Jowett; James Raftery; Stirling Bryan; Michael Davies; Gregory Lip
Journal:  BMC Cardiovasc Disord       Date:  2004-07-29       Impact factor: 2.298

  2 in total

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