| Literature DB >> 87627 |
D M Morens, R M Zweighaft, T M Vernon, G W Gary, J J Eslien, B T Wood, R C Holman, R Dolin.
Abstract
In December, 1976, an outbreak of gastroenteritis occurred at a resort camp in Colorado. Data obtained by questionnaire from 760 persons indicated that 418 (55%) had had gastroenteritis at the camp or within a week of leaving it, with peak onset within a two-day period. Symptoms included vomiting (81%), diarrhoea (65%), and fever (49%); median duration of illness was twenty-four hours. The attack-rate increased with consumption of water or ice-containing beverages. The camp water supply was found to be inadequately chlorinated and contaminated by a leaking septic tank. Although routine laboratory tests did not reveal bacterial, viral, or parasitic pathogens, immune electron microscopy detected virus-like particles in two of five diarrhoeal stool filtrates. Oral administration of one of these bacteria-free filtrates to two volunteers induced a gastrointestinal illness similar to that observed in the camp visitors.Entities:
Mesh:
Year: 1979 PMID: 87627 DOI: 10.1016/s0140-6736(79)91734-3
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321