Literature DB >> 8761419

Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures.

S M Clutton1, K M Townsend, C Walker, J D Ansell, E G Wright.   

Abstract

There is accumulating evidence that cells exposed to low and often environmentally relevant doses of ionizing radiation survive the initial insult, but transmit genomic instability to their progeny. The underlying mechanism of radiation-induced genomic instability is unknown. We present bio-chemical evidence consistent with the hypothesis that enhanced and persistent oxy-radical activity may be responsible.

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Year:  1996        PMID： 8761419     DOI： 10.1093/carcin/17.8.1633

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN： 0143-3334            Impact factor:   4.944


  42 in total

1.  Induction of chromosomal instability by chronic oxidative stress.

Authors:  Charles L Limoli; Erich Giedzinski
Journal:  Neoplasia       Date:  2003 Jul-Aug       Impact factor: 5.715

2.  Modeling cell response to low doses of photon irradiation: Part 2--application to radiation-induced chromosomal aberrations in human carcinoma cells.

Authors:  Micaela Cunha; Etienne Testa; Olga V Komova; Elena A Nasonova; Larisa A Mel'nikova; Nina L Shmakova; Michaël Beuve
Journal:  Radiat Environ Biophys       Date:  2015-12-26       Impact factor: 1.925

3.  Cytogenetic effects of low-dose radiation with different LET in human peripheral blood lymphocytes.

Authors:  E A Nasonova; N L Shmakova; O V Komova; L A Mel'nikova; T A Fadeeva; E A Krasavin; S Ritter
Journal:  Radiat Environ Biophys       Date:  2006-10-10       Impact factor: 1.925

Review 4.  Challenges and progress in predicting biological responses to incorporated radioactivity.

Authors:  R W Howell; P V S V Neti; M Pinto; B I Gerashchenko; V R Narra; E I Azzam
Journal:  Radiat Prot Dosimetry       Date:  2007-02-06       Impact factor: 0.972

Review 5.  Twilight effects of low doses of ionizing radiation on cellular systems: a bird's eye view on current concepts and research.

Authors:  Ilaria Postiglione; Angela Chiaviello; Giuseppe Palumbo
Journal:  Med Oncol       Date:  2009-06-06       Impact factor: 3.064

6.  A role for bioelectric effects in the induction of bystander signals by ionizing radiation?

Authors:  C Mothersill; G Moran; F McNeill; M D Gow; J Denbeigh; W Prestwich; C B Seymour
Journal:  Dose Response       Date:  2007-04-03       Impact factor: 2.658

7.  Sensitivity to low-dose/low-LET ionizing radiation in mammalian cells harboring mutations in succinate dehydrogenase subunit C is governed by mitochondria-derived reactive oxygen species.

Authors:  Nukhet Aykin-Burns; Benjamin G Slane; Annie T Y Liu; Kjerstin M Owens; Malinda S O'Malley; Brian J Smith; Frederick E Domann; Douglas R Spitz
Journal:  Radiat Res       Date:  2010-11-17       Impact factor: 2.841

8.  Chromosomal instability in the descendants of unirradiated surviving cells after alpha-particle irradiation.

Authors:  S A Lorimore; M A Kadhim; D A Pocock; D Papworth; D L Stevens; D T Goodhead; E G Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1998-05-12       Impact factor: 11.205

9.  A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability.

Authors:  Grace J Kim; Gary M Fiskum; William F Morgan
Journal:  Cancer Res       Date:  2006-11-01       Impact factor: 12.701

10.  Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase.

Authors:  Eun-Hee Hong; Su-Jae Lee; Jae-Sung Kim; Kee-Ho Lee; Hong-Duck Um; Jae-Hong Kim; Song-Ja Kim; Jong-Il Kim; Sang-Gu Hwang
Journal:  J Biol Chem       Date:  2009-11-03       Impact factor: 5.157
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