Literature DB >> 8749908

Hepatotoxicity of transplant immunosuppressive agents.

K V Kowdley1, E B Keeffe.   

Abstract

Hepatotoxicity from transplant immunosuppressive agents is infrequent but recognized. Most of the published literature emphasizes hepatotoxicity from cyclosporine and azathioprine. Cyclosporine is associated with cholestasis and possibly biliary calculi. Azathioprine has been associated with a variety of hepatic abnormalities. This article reviews the frequency and pattern of hepatotoxicity associated with these agents.

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Year:  1995        PMID： 8749908

Source DB:  PubMed          Journal:  Gastroenterol Clin North Am        ISSN： 0889-8553            Impact factor:   3.806


  8 in total

Review 1.  Drug-induced liver disorders: implications for drug development and regulation.

Authors:  N Kaplowitz
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

2.  The use of cyclosporine in a boy with a prior episode of posterior encephalopathy.

Authors:  Chieko Nakahara; Naoyuki Hasegawa; Isho Izumi; Katsuyosi Kanemoto; Nobuaki Iwasaki
Journal:  Pediatr Nephrol       Date:  2005-02-17       Impact factor: 3.714

3.  Cyclosporine A reduces dendritic outgrowth of neuroblasts in the subgranular zone of the dentate gyrus in C57BL/6 mice.

Authors:  In Koo Hwang; Sun Shin Yi; Jae Hoon Shin; Ki-Yeon Yoo; Jung Hoon Choi; Choong Hyun Lee; Je Kyung Seong; Yeo Sung Yoon; Jeong Ho Park; Moo-Ho Won
Journal:  Neurochem Res       Date:  2009-10-25       Impact factor: 3.996

Review 4.  Immunosuppressive therapy in older cardiac transplant patients.

Authors:  Arezu Zejnab Aliabadi; Andreas Oliver Zuckermann; Michael Grimm
Journal:  Drugs Aging       Date:  2007       Impact factor: 3.923

Review 5.  Diagnosis, pathogenesis, and treatment of autoimmune hepatitis after liver transplantation.

Authors:  Albert J Czaja
Journal:  Dig Dis Sci       Date:  2012-05-06       Impact factor: 3.199

6.  Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.

Authors:  W B Mattes; H G Kamp; E Fabian; M Herold; G Krennrich; R Looser; W Mellert; A Prokoudine; V Strauss; B van Ravenzwaay; T Walk; H Naraoka; K Omura; I Schuppe-Koistinen; S Nadanaciva; E D Bush; N Moeller; P Ruiz-Noppinger; S P Piccoli
Journal:  Biomed Res Int       Date:  2013-05-21       Impact factor: 3.411

Review 7.  Evaluation of elevated liver enzymes.

Authors:  Tae Hoon Lee; W Ray Kim; John J Poterucha
Journal:  Clin Liver Dis       Date:  2012-05       Impact factor: 6.126

8.  Estrogen-Estrogen Receptor α Signaling Facilitates Bilirubin Metabolism in Regenerating Liver Through Regulating Cytochrome P450 2A6 Expression.

Authors:  Ta-Lun Kao; Yao-Li Chen; Yu-Ping Kuan; Wei-Chun Chang; Yu-Chen Ho; Shuyuan Yeh; Long-Bin Jeng; Wen-Lung Ma
Journal:  Cell Transplant       Date:  2017-11       Impact factor: 4.064
  8 in total

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