Literature DB >> 8749111

In vivo regeneration of vestibular hair cells of guinea pig.

H Yamane1, T Nakagawa, H Iguchi, S Shibata, M Takayama, K Nishimura, Y Nakai.   

Abstract

Recent studies have shown that inner ear sensory cells may regenerate in mammals as well as in birds. In this in vivo study we investigated the regeneration of vestibular hair cells in guinea pigs after gentamycin intoxication, and found that the vestibular sensory epithelia reproduced new hair cells 30 days after degeneration, due to 30 consecutive days of gentamycin treatment. From the regeneration pattern of sensory epithelia, the supporting cells were identified as the progenitors of hair cells.

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Year:  1995        PMID: 8749111

Source DB:  PubMed          Journal:  Acta Otolaryngol Suppl        ISSN: 0365-5237


  8 in total

1.  Immunocytochemical and morphological evidence for intracellular self-repair as an important contributor to mammalian hair cell recovery.

Authors:  J L Zheng; G Keller; W Q Gao
Journal:  J Neurosci       Date:  1999-03-15       Impact factor: 6.167

2.  Eye-head coordination in the guinea pig I. Responses to passive whole-body rotations.

Authors:  N Shanidze; A H Kim; Y Raphael; W M King
Journal:  Exp Brain Res       Date:  2010-08-05       Impact factor: 1.972

3.  Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker.

Authors:  J L Zheng; W Q Gao
Journal:  J Neurosci       Date:  1997-11-01       Impact factor: 6.167

4.  Gentamicin ototoxicity induced apoptosis of the vestibular hair cells of guinea pigs.

Authors:  T Nakagawa; H Yamane; S Shibata; Y Nakai
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 2.503

5.  Temporal dynamics of semicircular canal and otolith function following acute unilateral vestibular deafferentation in humans.

Authors:  Jun-ru Tian; Akira Ishiyama; Joseph L Demer
Journal:  Exp Brain Res       Date:  2006-11-08       Impact factor: 1.972

Review 6.  Therapeutic potential of neurotrophins for treatment of hearing loss.

Authors:  W Q Gao
Journal:  Mol Neurobiol       Date:  1998       Impact factor: 5.590

7.  A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae.

Authors:  Amber D Slowik; Olivia Bermingham-McDonogh
Journal:  Dev Biol       Date:  2016-01-28       Impact factor: 3.582

8.  Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris.

Authors:  Makoto Kinoshita; Chisato Fujimoto; Shinichi Iwasaki; Akinori Kashio; Yayoi S Kikkawa; Kenji Kondo; Hideyuki Okano; Tatsuya Yamasoba
Journal:  Front Cell Neurosci       Date:  2019-10-25       Impact factor: 5.505

  8 in total

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